This dataset contains model-based ZIP Code tabulation Areas (ZCTA) level estimates for the PLACES project 2020 release in GIS-friendly format. The PLACES project is the expansion of the original 500 Cities project and covers the entire United States—50 states and the District of Columbia (DC)—at county, place, census tract, and ZIP Code tabulation Areas (ZCTA) levels. It represents a first-of-its kind effort to release information uniformly on this large scale for local areas at 4 geographic levels. Estimates were provided by the Centers for Disease Control and Prevention (CDC), Division of Population Health, Epidemiology and Surveillance Branch. The project was funded by the Robert Wood Johnson Foundation (RWJF) in conjunction with the CDC Foundation. Data sources used to generate these model-based estimates include Behavioral Risk Factor Surveillance System (BRFSS) 2018 or 2017 data, Census Bureau 2010 population estimates, and American Community Survey (ACS) 2014-2018 or 2013-2017 estimates. The 2020 release uses 2018 BRFSS data for 23 measures and 2017 BRFSS data for 4 measures (high blood pressure, taking high blood pressure medication, high cholesterol, and cholesterol screening). Four measures are based on the 2017 BRFSS data because the relevant questions are only asked every other year in the BRFSS. These data can be joined with the census 2010 ZCTA boundary file in a GIS system to produce maps for 27 measures at the ZCTA level. An ArcGIS Online feature service is also available at https://www.arcgis.com/home/item.html?id=8eca985039464f4d83467b8f6aeb1320 for users to make maps online or to add data to desktop GIS software.