This dataset accompanies proposed publication, "Tectonic disruption of the Proterozoic Yavapai-Matzatzal Province boundary near Sierra Hornaday, northwest Sonora", to be published in a Geological Society of America publication, which will report zircon SHRIMP-RG U-Pb ages and Sm-Nd whole rock isotope analyses to map the path of the Yavapai-Matzatzal province boundary across southwest Arizona and northwest Sonora. Samples were collected from the study area by Jon Nourse, Miguel Espinoza, and Erin Stahl (all of Cal. State Polytechnic Univ.), Karl Kellogg, Wayne Premo, Douglas Morton, Jonathan Matti, Barney Poole, and Alex Iriondo (all of the USGS), Thomas Anderson (Univ. of Pittsburgh), Leon Silver and Michael Oskin (all of Cal. Inst. Tech.), and Bryan Kriens (Cal. State Univ., Dominguez Hills), who brought them to the USGS Denver for analysis. The analyses were performed from Dec 2001 to August 2018.