* It is featured in the ''[[Half-Life]]'' series of games and in several of the ''[[Grand Theft Auto (series)|Grand Theft Auto]]'' games.
* It is the most powerful gun in the first ''[[Resident Evil]]'' game. It decapitated its target with a single shot. The character Barry Burton uses it as his main weapon.
* The "Cougar Magnum" in ''[[Goldeneye]]'' is modeled after it.
