Imaging particle analysis: Difference between revisions

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{{merge from|Micro-flow imaging|discuss=Talk:Imaging Particle Analysis#Dynamic imaging particle analysis#Proposed merge with Micro-flow imaging|date=January 2014}}
 
'''Imaging particle analysis''' is a technique for making particle measurements using [[digital imaging]], one of the techniques defined by the broader term [[particle size analysis]]. The measurements that can be made include [[particle size]], particle shape (morphology or [[shape analysis (digital geometry)|shape analysis]] and [[grayscale]] or [[RGB color model#Numeric representations|color]], as well as distributions (graphs) of [[Population (statistics)|statistical population]] measurements.
 
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The major advantage to dynamic image acquisition is that it enables acquiring and measuring particles at significantly higher speed, typically on the order of 10,000 particles/minute or greater. This means that statistically significant populations can be analyzed in far shorter time periods than previously possible with manual microscopy or even static imaging particle analysis. In this sense, dynamic imaging particle analysis systems combine the speed typical of [[particle counter]]s with the discriminatory capabilities of microscopy.<ref name=Brown />
 
===Micro-flow imaging===
''Micro-flow imaging (MFI)'' is a particle analysis technique that uses flow [[microscopy]] to quantify particles contained in a solution based on size. This technique is used in the [[biopharmaceutical]] industry to characterize subvisible particles from approximately 1 μm to >50 μm.<ref>{{cite journal | pmc = 2895433 | pmid=20517661 | doi=10.1208/s12248-010-9205-1 | volume=12 | title=Micro-flow imaging: flow microscopy applied to sub-visible particulate analysis in protein formulations | year=2010 | journal=AAPS J | pages=455–64 | last1 = Sharma | first1 = DK | last2 = King | first2 = D | last3 = Oma | first3 = P | last4 = Merchant | first4 = C}}</ref>
 
 
 
== References ==