DNA microarray: Difference between revisions

Revision as of 18:26, 9 December 2020

Revision as of 17:42, 28 December 2020

Line 154:

The advent of inexpensive microarray experiments created several specific bioinformatics challenges:{{citation needed|date=January 2019}} the multiple levels of replication in experimental design ([[#Experimental design|Experimental design]]); the number of platforms and independent groups and data format ([[#Standardization|Standardization]]); the statistical treatment of the data ([[#Data analysis|Data analysis]]); mapping each probe to the [[mRNA]] transcript that it measures ([[#Annotation|Annotation]]); the sheer volume of data and the ability to share it ([[#Data warehousing|Data warehousing]]).

=== Experimental designdesi ===

Due to the biological complexity of gene expression, the considerations of experimental design that are discussed in the [[expression profiling]] article are of critical importance if statistically and biologically valid conclusions are to be drawn from the data.