Talk:SNP array: Difference between revisions

Revision as of 10:17, 4 November 2011

Latest revision as of 20:54, 27 January 2024

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=Probes <-> Targets=

{{WikiProject ComputationalMolecular Biology|classCOMPBIO=Byes|COMPBIO-importance=high|MCB=yes |MCB-importance=Mid }}

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==Sentence issue==

"As SNPs are highly conserved throughout evolution and within a population..."- an incorrect sentence. SNPs are not highly conserved, most SNPs fall outside coding sequences and outside regulatory regions, most SNPs are in nonfunctional DNA and evolving neutrally, only a small minority of SNPs are under selection. Also it makes little sense to say "SNPs are highly conserved throughout evolution" because SNPs are by definition intra-species variation (that's what a polymorphism is). If a SNP was "highly conserved" then it would be the same nucleotide in every individual of a species and across multiple species, but then it would no longer be classified as a SNP as it would be fixed in the population/species. The 2nd half of the sentence, "the map of SNPs serves as an excellent genotypic marker for research", has no clear meaning. I suggest the whole sentence is removed.

-End of rant- <small class="autosigned">—&nbsp;Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/131.111.176.16|131.111.176.16]] ([[User talk:131.111.176.16|talk]]) 10:51, 4 February 2015 (UTC)</small><!-- Template:Unsigned IP --> <!--Autosigned by SineBot-->

==Probes <-> Targets==

[[File:NA hybrid.svg|thumb|400px|Hybridization of the target to the probe.]]

I think that probe and target are mixed up in the explanation (Section: Principles).

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[[Special:Contributions/134.99.165.175|134.99.165.175]] ([[User talk:134.99.165.175|talk]]) 10:17, 4 November 2011 (UTC)

I agree that this is backwards, and will fix it.

=Project Scopes=

[[User:Mkkuhner|Mkkuhner]] ([[User talk:Mkkuhner|talk]]) 21:18, 2 February 2015 (UTC)

{{Wikiproject MCB|importance=Mid|class=Start}}

{{WikiProject Computational Biology|class=B|importance=high}}

==Pronunciation question==

Do you say "S-N-P" or "snip"? <span style="font-size: smaller;" class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/92.213.30.142|92.213.30.142]] ([[User talk:92.213.30.142|talk]]) 19:40, 20 May 2014 (UTC)</span><!-- Template:Unsigned IP --> <!--Autosigned by SineBot-->

Researchers in the field say "snip." [[User:Mkkuhner|Mkkuhner]] ([[User talk:Mkkuhner|talk]]) 21:18, 2 February 2015 (UTC)