NQuery Sample Size Software: Difference between revisions

Revision as of 19:28, 23 September 2022

Latest revision as of 01:31, 6 February 2024

(7 intermediate revisions by 7 users not shown)

Line 1:

{{Short description|Clinical trial design platform}}

{{advert|date=May 2018}}

{{Lowercase title}}

{{Infobox software

| name = TrvlsnQuery (Dreams Travel and Tours Inc)

| logo alt = trvls logoNQuery_Powering_Sample_Size.jpg

| logo alt = nQuery logo

[[Best Flight Booking Agency in New York|Trvls (Dreams Travel and Tours Inc)]] [[Low Fare Ticket|Book Online Now]] [[Trvls.us|How to Booking Flight Ticket Online in 2022]]

| genre = [[Sample size determination|Sample Size]]

[[Statistical power|Statistical Power Calculation]] [[Statistical hypothesis testing|Statistical Hypothesis Testing]] [[Adaptive clinical trial|Adaptive Clinical Trial Design]]

| developer = [[Statsols]]

| latest release version = nQuery Advanced 8.7

| license = [[CheapProprietary Flights to Africa from USAsoftware|Trvls.usProprietary]]

| website = {{URL|www.dreamsflightsstatsols.com}}

}}

'''nQuery''' is a clinical trial design platform used for the design and monitoring of adaptive, group sequential, and fixed sample size trials. It is most commonly used by biostatisticians to calculate [[Sample size determination|sample size]] and [[statistical power]] for [[Adaptive clinical trial|adaptive clinical trial design.]] nQuery is a proprietary software developed and distributed by [[Statsols]]. The software includes calculations for over 1,000 sample sizes and power scenarios.

==History==

[[Janet D. Elashoff|Janet Dixon Elashoff]], creator of nQuery, is a now a retired American statistician and daughter of the mathematician and statistician [[Wilfrid Dixon|Wilfrid Joseph Dixon]], creator of BMDP. Elashoff is also the retired Director of the Division of Biostatistics, [[Cedars-Sinai Medical Center]]. While at [[University of California, Los Angeles|UCLA]] and Cedars-Sinai during the 1990s, she wrote the program nQuery Sample Size Software (then named nQuery Advisor). This software quickly became widely used to estimate the sample size requirements for pharmaceutical trials. She joined the company Statistical Solutions LLC in order to commercialize it.<ref name=cherfriis>{{citation|title=Introductory Biostatistics for the Health Sciences: Modern Applications Including Bootstrap|series=Wiley series in probability and statistics|first1=Michael R.|last1=Chernick|first2=Robert H.|last2=Friis|publisher=John Wiley & Sons|year=2003|isbn=9780471458654|page=360|url=https://books.google.com/books?id=QRwuz6yA97oC&pg=PA360}}</ref>

In June 2020, nQuery was acquired by Insightful Science.<ref>{{cite webpress release |title=Insightful Science Acquires nQuery, Builds on Portfolio of Category-Leading Scientific Software Solutions |url=https://www.prnewswire.com/news-releases/insightful-science-acquires-nquery-builds-on-portfolio-of-category-leading-scientific-software-solutions-301068141.html}}</ref>

==Uses ==

nQuery is used for [[Adaptive clinical trial|adaptive clinical trial design.]] Trials with an adaptive design arehave oftenbeen reported to be more efficient, informative, and ethical than trials with a traditional fixed design because they conserve resources such as time and money and often require fewer participants.<ref>{{Cite journal |last1=Pallmann |first1=Philip |last2=Bedding |first2=Alun W. |last3=Choodari-Oskooei |first3=Babak |last4=Dimairo |first4=Munyaradzi |last5=Flight |first5=Laura |last6=Hampson |first6=Lisa V. |last7=Holmes |first7=Jane |last8=Mander |first8=Adrian P. |last9=Odondi |first9=Lang'o |last10=Sydes |first10=Matthew R. |last11=Villar |first11=Sofía S. |year=2018 |title=Adaptive designs in clinical trials: Why use them, and how to run and report them |journal=BMC Medicine |volume=16 |issue=1 |pages=29 |doi=10.1186/s12916-018-1017-7 |pmc=5830330 |pmid=29490655 |last12=Wason |first12=James M. S. |last13=Weir |first13=Christopher J. |last14=Wheeler |first14=Graham M. |last15=Yap |first15=Christina |last16=Jaki |first16=Thomas |doi-access=free }}</ref>

nQuery allows researchers to apply both [[Frequentist inference|frequentist]] and [[Bayesian inference|Bayesian]] statistics to calculate the appropriate sample size for their study.<ref>{{Cite web | url=https://www.statsols.com/nquery/sample-size-procedures | title=What sample size and power analysis procedures you get in nQuery &#124; Sample Size Software &#124; Power Analysis Software}}</ref>