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<noinclude>{{Utente:Vale maio/Disclaimer}}</noinclude>
=[[en:Bulbous corpuscle]]=
 
=[[Corpuscolo di Ruffini]]=
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{{anatomia
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Il '''corpuscolo di Ruffini''' è una classe di [[meccanorecettore|meccanorecettori]] ad adattamento lento. Si pensa che siano presenti solo nelle zone naturalmente glabre del [[derma]] (dorso della [[mano]], pianta del [[Piede (anatomia)|piede]], [[labbro|labbra]], [[piccole labbra]] e [[glande]]), e nell'[[ipoderma]] umano. Il nome deriva dal medico italiano [[Angelo Ruffini]].
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==Function==
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This spindle-shaped receptor is sensitive to skin stretch, and contributes to the kinesthetic sense of and control of finger position and movement.<ref>{{Cita libro|cognome=Mountcastle |nome=Vernon C. |anno=2005 |titolo=The Sensory Hand: Neural Mechanisms of Somatic Sensation |editore=Harvard University Press |p=34}}</ref> It is believed to be useful for monitoring slippage of objects along the surface of the skin, allowing modulation of grip on an object.
Ruffinian endings are located in the deep layers of the skin, and register mechanical deformation within joints, more specifically angle change, with a specificity of up to 2 degrees, as well as continuous pressure states.They also act as a thermoreceptors that respond for a long time, so in case of deep burn there will be no pain as these receptors will be burned off.<ref>{{Cita libro|cognome=Hamilton |nome=Nancy |anno=2008 |titolo=Kinesiology: Scientific Basis of Human Motion |editore=McGraw-Hill |pp=76–7}}</ref>
 
==Footnotes and references==
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==External links==
* {{Cita pubblicazione|autore= Paré M, Behets C, Cornu O |titolo= Paucity of presumptive ruffini corpuscles in the index finger pad of humans. |rivista= J Comp Neurol |volume= 456 |numero= 3 |pp= 260–6 |anno= 2003 | pmid = 12528190 | doi = 10.1002/cne.10519}}
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<center>in milioni di anni</center>
 
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from: -359.2 till: -299 text:[[Carboniferous]] color:carboniferous
from: -416 till: -359.2 text:[[Devonian]] color:devonian
from: -443.7 till: -416 text:[[Silurian|Sil-~urian]] shift:(0,0.5) color:silurian
from: -488.3 till: -443.7 text:[[Ordovician]] color:ordovician
from: -542 till: -488.3 text:[[Cambrian]] color:cambrian
</timeline>
 
<timeline>
ImageSize = width:800 height:100
PlotArea = left:65 right:15 bottom:20 top:5
AlignBars = justify
 
Colors =
id:quaternary value:rgb(0.9,0.9,0.5)
id:neogene value:rgb(0.99215,0.8,0.54)
id:paleogene value:rgb(1,0.7019,0)
id:cenozoic value:rgb(1,1,0)
id:holocene value:rgb(1,1,0.702)
id:pleistocene value:rgb(1,0.922,0.384)
id:pliocene value:rgb(1,0.922,0.675)
id:miocene value:rgb(1,0.871,0)
id:oligocene value:rgb(0.918,0.776,0.447)
id:eocene value:rgb(0.918,0.678,0.263)
id:paleocene value:rgb(0.92,0.576,0.005)
id:black value:black
id:white value:white
id:darkgreen value:rgb(0,0.35,0)
 
Period = from:-65.5 till:0
TimeAxis = orientation:horizontal
ScaleMajor = unit:year increment:10 start:-60
ScaleMinor = unit:year increment:1 start:-65
 
Define $markgreen = text:"*" textcolor:darkgreen shift:(0,3) fontsize:10
 
PlotData=
align:center textcolor:black fontsize:8 mark:(line,black) width:25 shift:(0,-5)
 
bar:era
at: 0 align:right $markgreen
at: start align:left $markgreen shift:(2,3)
from:start till: 0 text:[[Cenozoic]] color:cenozoic
 
bar:period
from: -2.588 till: 0 text:[[Quaternary|Q.]] color:quaternary
from: -23.03 till: -2.588 text:[[Neogene]] color:neogene
from:start till: -23.03 text:[[Paleogene]] color:paleogene
 
bar:epoch
from: -0.1 till: 0 color:holocene
from: -2.588 till: -0.1 text:[[Pleistocene|P]] color:pleistocene
from: -5.332 till: -2.588 text:[[Pliocene|Plio-~cene]] shift:(0,1) color:pliocene fontsize:7
from:-23.03 till: -5.332 text:[[Miocene]] color:miocene
from:-33.9 till:-23.03 text:[[Oligocene]] color:oligocene
from:-55.8 till:-33.9 text:[[Eocene]] color:eocene
from:start till:-55.8 text:[[Paleocene]] color:paleocene
</timeline>