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=== BioArchLinux ===
[https://github.com/BioArchLinux/Packages BioArchLinux repository] contain more than 3,770 packages for Arch Linux and Arch Linux based distribution. <ref name="Zhang 2025">{{Cite journal|last1=Zhang|first1=Guoyi|last2=Ristola|first2=Pekka|last3=Su|first3=Han|last4=Kumar|first4=Bipin|last5=Zhang|first5=Boyu|last6=Hu|first6=Yujin|last7=Elliot|first7=Michael G|last8=Drobot|first8=Viktor|last9=Zhu|first9=Jie|last10=Staal|first10=Jens|last11=Larralde|first11=Martin|last12=Wang|first12=Shun|last13=Yi|first13=Yun|last14=Yu|first14=Haoran|date=2025|title=BioArchLinux: community-driven fresh reproducible software repository for life sciences|journal=Bioinformatics|pages=btaf106|doi=10.1093/bioinformatics/btaf106|issn=1367-4811|doi-access=free|pmc=11925497}}</ref>
[https://github.com/BioArchLinux/Packages BioArchLinux repository] contain more than 3,770 packages for Arch Linux and Arch Linux based distribution.
 
=== Debian ===
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; FreeBSD
 
[[FreeBSD]] is not a Linux distribution, but a version of [[BSD|Unix]] that it is very similar. Its [[ports collection|ports]] are analogous Gentoo's ebuilds. However, the project continuously builds pre-compiled binary packages for Tier-1 platforms such as [[x86]] and [[ARM_architecture_family|ARM]]. ThereUsers arecan overalso 240choose biologicalto sciencesbuild applicationsand amonginstall overany 2,200port scientificfrom applicationssource andin overorder 31,000to portsenable innon-portable generaloptimizations or other build options. NewThe build-from-source option also allows the ports andsystem updatesto areautomate listedinstallation onof thesoftware Freshwith Ports<ref>[http://www.freshports.org/biology/a Freshlicense Ports]</ref>that does not permit siteredistribution.
 
The ports collection contains over 31,000 ports, of which over 2,200 are in scientific categories, and over 240 are biology-related. New ports and updates are listed on the Fresh Ports<ref>[http://www.freshports.org/biology/ Fresh Ports]</ref> site.
 
; pkgsrc
 
The [[pkgsrc]] package manager, originally forked from [[FreeBSD ports]], is maintained by the [[NetBSD]] project, but aims to support all [[POSIX]]-compatible operating systems. It is well-tested on [[NetBSD]], many [[Linux]] distributions, [[macOS]], and [[SunOS]] derivatives. Like FreeBSD ports, pre-compiled binary packages are maintained for some platforms. Packages can be built from source on any platform, or if additional optimizations or options are desired. The pkgsrc collection contains over 19,000 packages, of which nearly 800 are in scientific categories, and over 60 are biology-related.
 
; Debian
 
There are more than a hundred bioinformatics packages provided as part of the standard Debian installation. NEBC Bio-Linux<ref>[{{Cite web |url=http://envgen.nox.ac.uk/biolinux.html |title=NEBC Bio-Linux] |access-date=2005-12-19 |archive-date=2006-04-22 |archive-url=https://web.archive.org/web/20060422152024/http://envgen.nox.ac.uk/biolinux.html |url-status=dead }}</ref> packages can also be installed on a standard Debian system as long as the bio-linux-base package is also installed. This creates a /usr/local/bioinf directory where our other packages install their software. Debian packages may also work on [[Ubuntu Linux]] or other Debian-derived installations.
 
== Community building and support systems ==