Single particle extinction and scattering: Difference between revisions

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{{Short description|Physics technique}}

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'''Single Particle Extinction and Scattering''' (also known as '''SPES''') is a technique in [[physics]] that can be used to characterise micro and [[nanoparticle|nanoparticles]] in suspension in a fluid through two independent parameters, the diameter and the [[refractive index|effective refractive index]].

'''Single Particle Extinction and Scattering (SPES)''' is a technique in [[physics]] that is used to characterise micro and [[nanoparticle]]s suspended in a fluid through two independent parameters, the diameter and the [[refractive index|effective refractive index]].<ref>{{Cite journal |title=Single particle extinction and scattering optical method unveils in real time the influence of the blood components on polymeric nanoparticles |journal = Nanomedicine: Nanotechnology, Biology and Medicine|volume = 13|issue = 8|last1=Sanvito |first1=Tiziano |last2=Bigini |first2=Paolo |date=November 2017 |pages=2597–2603 |doi=10.1016/j.nano.2017.07.008 |pmid=28756089 |last3=Cavanna |first3=Maria V. |last4=Fiordaliso |first4=Fabio |last5=Violatto |first5=Martina B. |last6=Talamini |first6=Laura |last7=Salmona |first7=Mario |last8=Milani |first8=Paolo |last9=Potenza |first9=Marco A. C.}}</ref><ref>{{Cite journal |title=Detecting the shape of anisotropic gold nanoparticles in dispersion with single particle extinction and scattering |last1=Dawson |first1=K. A. |last2=Milani |first2=P. |date=2017-02-23 |journal=Nanoscale |volume=9 |issue=8 |pages=2778–2784 |language=en |doi=10.1039/C6NR08977A |last3=Castagnola |first3=V. |last4=Boselli |first4=L. |last5=Cella |first5=C. |last6=Araújo |first6=J. M. de |last7=Monopoli |first7=M. |last8=Cai |first8=Q. |last9=Sanvito |first9=T.|pmid=28155930 |doi-access=free |hdl=2434/701388 |hdl-access=free }}</ref>

A [[laser]] generate a [[gaussian beam]] which focuses inside a flow cell. A particle who passes in the focal region generates an interference in the beam, which is collected with a sensor. Trough this signal it is possible to derive the real part and the immaginary part of the forward scattering field, from each single particle.

A [[laser]] generategenerates a [[gaussian beam]] which focuses inside a flow cell. A particle whothat passes inthrough the focal region generates an interference in the beam, which is collected with a sensor. TroughThrough this signal it is possible to derive the real part and the immaginaryimaginary part of the forward scattering field, from each single particle.

The technique was developed to measure aerosols in air<ref>{{Cite journal |doi = 10.1007/s11051-017-3995-3|title = Single Particle Extinction and Scattering allows novel optical characterization of aerosols|journal = Journal of Nanoparticle Research|volume = 19|issue = 8|pages = 291|year = 2017|last1 = Mariani|first1 = Federico|last2 = Bernardoni|first2 = Vera|last3 = Riccobono|first3 = Francesco|last4 = Vecchi|first4 = Roberta|last5 = Valli|first5 = Gianluigi|last6 = Sanvito|first6 = Tiziano|last7 = Paroli|first7 = Bruno|last8 = Pullia|first8 = Alberto|last9 = Potenza|first9 = Marco A. C.|bibcode = 2017JNR....19..291M|s2cid = 139469999}}</ref> and particles in liquid.<ref>{{Cite journal |title=Single particle optical extinction and scattering allows real time quantitative characterization of drug payload and degradation of polymeric nanoparticles |last1=Milani |first1=P. |last2=Lenardi |first2=C. |date=2015-12-15 |journal=Scientific Reports |volume=5 |pages=18228 |doi=10.1038/srep18228 |pmid=26667064 |last3=Paroli |first3=B. |last4=Cella |first4=C. |last5=Argentiere |first5=S. |last6=Sanvito |first6=T. |last7=Potenza |first7=M. a. C.|bibcode=2015NatSR...518228P |pmc=4678328 }}</ref>

The technique was developed to measure aerosols in air<ref>https://doi.org/10.1007/s11051-017-3995-3</ref> and particles in liquid<ref>url=https://www.nature.com/articles/srep18228</ref>.

== References ==

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[[Category:Experimental physics]]

[[Category:Laser science]]

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