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{{Short description|Agricultural system}}
The '''Enlist Weed Control System''' is an [[agriculture|agricultural]] system that includes seeds for [[genetically modified crops]] that are resistant to Enlist (a broadleaf [[herbicide]] with two active agents, [[2,4-Dichlorophenoxyacetic acid]] (2,4-D) and [[glyphosate]]) and the Enlist herbicide; spraying the herbicide will kill weeds but not the resulting crop.<ref name=reuters/><ref>{{cite web |url=http://farmprogress.com/story-usda-releases-draft-environmental-impact-statement-dows-enlist-13-106875| author= |title=USDA Releases Draft Environmental Impact Statement on Dow's Enlist|publisher=American Agriculturist| date=January 3, 2014 |accessdateaccess-date=May 3, 2014|archive-url=https://web.archive.org/web/20140110184955/http://farmprogress.com/story-usda-releases-draft-environmental-impact-statement-dows-enlist-13-106875|archive-date=January 10, 2014|url-status=dead}}</ref> The system was developed by [[Dow AgroSciences]], part of [[Dow Chemical Company]].<ref name=reuters>{{cite news| url=httphttps://www.reuters.com/article/2014/03/10/us-agriculture-dow-enlist-insight-idUSBREA290HU20140310 |author=Carey Gilliam| title=As Dow seeks growth, new Enlist crop/chemicals seen as key| publisher=[[Reuters]] |date=March 10, 2014 |accessdateaccess-date=May 3, 2014}}</ref> In October 2014 the system was registered for restricted use in Illinois, Indiana, Iowa, Ohio, South Dakota and Wisconsin by the [[US Environmental Protection Agency]].<ref>{{Cite news|url = http://deltafarmpress.com/corn/enlist-duo-approved-six-states-restrictions|title = Enlist Duo approved in six states, with restrictions|last = |first = |date = October 15, 2014|work = Delta Farm Press|accessdateaccess-date = October 17, 2014}}</ref> In 2013, the system was approved by Canada for the same uses.<ref>{{Cite web|url = httphttps://www2www.epa.gov/ingredients-used-pesticide-products/registration-enlist-one-and-enlist-duo|title = Registration of Enlist Duo|date = October 2014|accessdateaccess-date = October 17, 2014|website = EPA|publisher = Environmental Protection Agency|last = EPA|firstarchive-date = December 16, 2021|archive-url = https://web.archive.org/web/20211216074048/https://www.epa.gov/ingredients-used-pesticide-products/registration-enlist-duo|url-status = live}}</ref>
 
The Enlist approach was developed to replace the "Roundup-Ready" system that was introduced in 1996 by [[Monsanto]] and which has become less useful with the rise of glyphosate-resistant weeds.<ref name=reuters/>
 
==''Enlist Duo''==
''Enlist Duo'' is an [[herbicide]] that contains the choline form of [[2,4-Dichlorophenoxyacetic acid]] (2,4-D) and [[glyphosate]] plus an unknown number of unlisted ingredients. Dow added chemicals to the mixture in what it termed "Colex-D technology" intended to reduce physical drift, ultraviolet volatility and odor and to improve handling.<ref name=farmfuture>{{cite web| url=http://farmfutures.com/story-epa-consider-comments-registration-enlist-duo-herbicide-0-111931| author= |title=EPA to Consider Comments on Registration of Enlist Duo Herbicide| publisher=Farm Futures| date=May 1, 2014| access-date=May 3, 2014|accessdate archive-url=https://web.archive.org/web/20140503160956/http://farmfutures.com/story-epa-consider-comments-registration-enlist-duo-herbicide-0-111931| archive-date=May 3, 2014| url-status=dead}}</ref>
 
2,4-D is one of the most widely used herbicides in the world.<ref>von Stackelberg K. A Systematic Review of Carcinogenic Outcomes and Potential Mechanisms from Exposure to 2,4-D and MCPA in the Environment. J Toxicol. 2013;2013:371610. {{PMID |23533401}} [http://www.hindawi.com/journals/jt/2013/371610/ PMC 3600329]</ref><ref>Andrew Pollack for the New York Times. April 9, 2012 [httphttps://www.nytimes.com/2012/04/10/business/energy-environment/epa-denies-request-to-ban-24-d-a-popular-weed-killer.html?_r=0 E.P.A. Denies an Environmental Group’s Request to Ban a Widely Used Weed Killer]</ref> 2,4-D is volatile and by EPA assessment is a hazardous air pollutant that is difficult to contain.{{CN|date=December The2015}} possibilityAccording of herbicide drift is whyto Dow developed, the Colex-D technology, which according to their experiments, significantlyformulation reduces drift and damage from evaporation.<ref>Josh Flint for Prairie Farmer. August 31, 2011 [http://farmprogress.com/story-dow-agrosciences-names-its-newest-herbicide-offering-duo-0-52677 Dow AgroSciences Names Its Newest Herbicide Offering Enlist Duo] {{Webarchive|url=https://web.archive.org/web/20140504025154/http://farmprogress.com/story-dow-agrosciences-names-its-newest-herbicide-offering-duo-0-52677 |date=2014-05-04 }}</ref> As of 2013 glyphosate was the world's largest-selling herbicide, with sales driven by glyphosate-resistant [[genetically modified crops]].<ref>China Research & Intelligence, June 5, 2013. [http://www.shcri.com/agricultural-chemicals/14-research-report-on-global-and-china-glyphosate-industry-2013-2017.html Research Report on Global and China Glyphosate Industry, 2013-2017] {{Webarchive|url=https://web.archive.org/web/20160303222042/http://www.shcri.com/agricultural-chemicals/14-research-report-on-global-and-china-glyphosate-industry-2013-2017.html |date=2016-03-03 }}</ref>
 
Other countries assessing the system include Brazil, Argentina and various food importing countries.<ref name=fleury>{{cite web | url=http://www.agannex.com/energy/enlist-weed-control-system-in-canada | author=Donna Fleury | title=Enlist weed control system in Canada. A new tool for managing hard to control and resistant weeds | publisher=AG Annex | date=April 2014 | accessdateaccess-date=May 3, 2014 | archive-date=October 25, 2015 | archive-url=https://web.archive.org/web/20151025023916/http://www.agannex.com/energy/enlist-weed-control-system-in-canada | url-status=dead }}</ref>
 
==Enlist crops==
As of April 2014 maize and soybeans resistant to 2,4-D and glyphosate had been approved in Canada,<ref name=fleury/> and in September 2014 the [[USDA]] approved the same two crops.<ref name=wired>{{cite newsmagazine|author1=Brandon Keim|title=New Generation of GM Crops Puts Agriculture in a ‘Crisis'Crisis Situation’Situation'|url=httphttps://www.wired.com/2014/09/new-gm-crops/|accessdateaccess-date=13 April 2015|workmagazine=Wired|publisher=Condé Nast.|date=25 September 2014}}</ref><ref name=ISAAAaad1>ISAAA GM Approval Database [http://www.isaaa.org/gmapprovaldatabase/gene/default.asp?GeneID=88&Gene=aad-1 GM Approval Database Genes List, Gene: aad1]. International Service for the Acquisition of Agri-biotech Applications (ISAAA), n.d. accessed February 27, 2015</ref>
 
==Criticism==
2,4-D was one of the main ingredients of [[Agent Orange]], a defoliant used during the [[Vietnam War]] that was blamed for many health problems.<ref name=NPIC2>{{cite web |title=2,4-D General Fact Sheet |url=http://npic.orst.edu/factsheets/24Dgen.html|publisher=National Pesticide Information Center |access-date=15 December 2015}}</ref> According to a Reuters article the Themain health problems arose from [[2,3,7,8-Tetrachlorodibenzodioxin|dioxinTCDD]] contamination created in the synthesis of the other Agent Orange component, [[2,4,5-T]], not from 2,4,-D, but the association nonetheless caused alarm.<ref name=gillam>{{cite web | url=httphttps://www.cornucopiareuters.orgcom/2013article/01/dowsdow-controversialbiotech-new-gmo-corn-delayed-amid-protests/idUSL1E9CIBN320130118 | authorpublisher=Reuters Carey Gillam| title=Dow’sDow's Controversial New GMO Corn Delayed Amid Protests|publisher=The Cornucopia Institute| dateyear=January 28, 2013 |accessdate=May 3, 2014}}</ref>
 
The [[U.S. Environmental Protection Agency]] has moved to rescind its approval of use {{mdash}} in part due to conflicting claims: (1) tofrom the EPAmanufacturer about synergistic effects from mixing the unchangedtwo harmlessnessherbicides. ofDow had told the EPA that the combination of the two defoliants'herbicides anddid (2)not thoseenhance intheir thetoxicity to plants, but an earlier [[Patentpatent application]] assertingfrom theDow enhancedclaimed "synergisticthat effectit did."<ref name="NPR">{{cite news |first1=Dan |last1=Charles |publisher=[[National Public Radio]] |title=Busted: EPA discovers DOW weedkiller claim; wants it off the market |url=httphttps://www.npr.org/sections/thesalt/2015/11/25/457393114/busted-epa-discovers-dow-weedkiller-claim-wants-it-off-the-market |date=November 25, 2015 |accessdateaccess-date=November 25, 2015}}</ref>
 
==External links==
* [http://www.enlist.com/ Enlist Weed Control System]
* [http://www.epa.gov/pesticides/factsheets/2-4-d-glyphosate.html EPA Factsheet]
 
==References==
{{reflist|2}}
 
==External links==
* [http://www.enlist.com/ Enlist Weed Control System]
* [https://archive.today/20140503183130/http://www.epa.gov/pesticides/factsheets/2-4-d-glyphosate.html EPA Factsheet]
 
[[Category:Herbicides]]