Endothelin converting enzyme 1: Difference between revisions

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{{Short description|Mammalian protein found in Homo sapiens}}

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{{Infobox_gene}}

'''<span lang="fr" dir="ltr">Endothelin</span> converting enzyme 1''', also known as '''ECE1''', is an [[enzyme]] which in humans is encoded by the ''ECE1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ECE1 endothelin converting enzyme 1| url = https://www.ncbi.nlm.nih.gov/sites/entrezgene?Db=gene&Cmd=ShowDetailView&TermToSearch=1889}}</ref><ref name="pmid7805846">{{cite journal | vauthors = Schmidt M, Kröger B, Jacob E, Seulberger H, Subkowski T, Otter R, Meyer T, Schmalzing G, Hillen H | title = Molecular characterization of human and bovine endothelin converting enzyme (ECE-1) | journal = FEBS Lett. | volume = 356 | issue = 2–3 | pages = 238–43 |date=December 1994 | pmid = 7805846 | doi = 10.1016/0014-5793(94)01277-6| doi-access = free }}</ref><ref name="pmid7864876">{{cite journal | vauthors = Shimada K, Matsushita Y, Wakabayashi K, Takahashi M, Matsubara A, Iijima Y, Tanzawa K | title = Cloning and functional expression of human endothelin-converting enzyme cDNA | journal = Biochem. Biophys. Res. Commun. | volume = 207 | issue = 2 | pages = 807–12 |date=February 1995 | pmid = 7864876 | doi = 10.1006/bbrc.1995.1258 | doi-access = free }}</ref>

== Function ==

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*{{cite journal | vauthors=Yorimitsu K, Moroi K, Inagaki N |title=Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2 |journal=Biochem. Biophys. Res. Commun. |volume=208 |issue= 2 |pages= 721–7 |year= 1995 |pmid= 7695628 |doi=10.1006/bbrc.1995.1397 |display-authors=etal}}

*{{cite journal | vauthors=Schmidt M, Kröger B, Jacob E |title=Molecular characterization of human and bovine endothelin converting enzyme (ECE-1) |journal=FEBS Lett. |volume=356 |issue= 2–3 |pages= 238–43 |year= 1995 |pmid= 7805846 |doi=10.1016/0014-5793(94)01277-6 |display-authors=etal|doi-access=free }}

*{{cite journal | vauthors=Shimada K, Matsushita Y, Wakabayashi K |title=Cloning and functional expression of human endothelin-converting enzyme cDNA |journal=Biochem. Biophys. Res. Commun. |volume=207 |issue= 2 |pages= 807–12 |year= 1995 |pmid= 7864876 |doi= 10.1006/bbrc.1995.1258 |display-authors=etal|doi-access=free }}

*{{cite journal | vauthors=Valdenaire O, Rohrbacher E, Mattei MG |title=Organization of the gene encoding the human endothelin-converting enzyme (ECE-1) |journal=J. Biol. Chem. |volume=270 |issue= 50 |pages= 29794–8 |year= 1996 |pmid= 8530372 |doi=10.1074/jbc.270.50.29794 |doi-access=free }}

*{{cite journal | vauthors=Matsuoka R, Sawamura T, Yamada K |title=Human endothelin converting enzyme gene (ECE1) mapped to chromosomal region 1p36.1 |journal=Cytogenet. Cell Genet. |volume=72 |issue= 4 |pages= 322–4 |year= 1996 |pmid= 8641140 |doi=10.1159/000134214 |display-authors=etal}}

*{{cite journal | vauthors=Orzechowski HD, Richter CM, Funke-Kaiser H |title=Evidence of alternative promoters directing isoform-specific expression of human endothelin-converting enzyme-1 mRNA in cultured endothelial cells |journal=J. Mol. Med. |volume=75 |issue= 7 |pages= 512–21 |year= 1997 |pmid= 9253714 |doi=10.1007/s001090050136 |s2cid=34633812 |display-authors=etal}}

*{{cite journal | vauthors=Schweizer A, Valdenaire O, Nelböck P |title=Human endothelin-converting enzyme (ECE-1): three isoforms with distinct subcellular localizations |journal=Biochem. J. |volume=328 |issue= Pt 3|pages= 871–7 |year= 1998 |pmid= 9396733 |doi= 10.1042/bj3280871| pmc=1218999 |display-authors=etal}}

*{{cite journal | vauthors=Kido T, Sawamura T, Masaki T |title=The processing pathway of endothelin-1 production |journal=J. Cardiovasc. Pharmacol. |volume=31 |pages= S13–5 |year= 1998 |issue=Suppl 1 |pmid= 9595387 |doi=10.1097/00005344-199800001-00006 |doi-access=free }}

*{{cite journal | vauthors=Hofstra RM, Valdenaire O, Arch E |title=A loss-of-function mutation in the endothelin-converting enzyme 1 (ECE-1) associated with Hirschsprung disease, cardiac defects, and autonomic dysfunction |journal=Am. J. Hum. Genet. |volume=64 |issue= 1 |pages= 304–8 |year= 1999 |pmid= 9915973 |doi=10.1086/302184 | pmc=1377732 |display-authors=etal}}

*{{cite journal | vauthors=Lee S, Lin M, Mele A |title=Proteolytic processing of big endothelin-3 by the kell blood group protein |journal=Blood |volume=94 |issue= 4 |pages= 1440–50 |year= 1999 |pmid= 10438732 |doi= 10.1182/blood.V94.4.1440|display-authors=etal}}