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::Other than ultraconserved regions, what other material in this article isn't covered just as well in another article? Regulatory sequences? Transposable elements? Pseudogenes? Introns? UTRs? [[User:Genome42|Genome42]] ([[User talk:Genome42|talk]]) 22:27, 24 July 2025 (UTC)
:::In that case, let's open discussion on what should be contained in the ideal article on CNEs and adjust or delete sections accordingly. Maybe shift focus away from where CNEs are located (which the article's organization emphasizes) towards their significance and functions/applications. In particular, the lead mentions comparative genomics, which could be one avenue of approach — [[User:VolatileAnomaly|<b style="background-color:black;border:3px solid gray;padding:3px;color:lime;">🪫Volatile</b>]] <sup>[[User talk:VolatileAnomaly|''' 📲T''']] | [[Special:Contributions/VolatileAnomaly|'''⌨️C''']]</sup> 06:19, 27 July 2025 (UTC)
::::Are you suggesting that we rename the article to "Conserved non-coding elements (CNEs)" and confine the material to a discussion about ultraconserved non-coding regions?
:::::"Comparative genomics has revealed a class of non-protein-coding genomic sequences that display an extraordinary degree of conservation between two or more organisms, regularly exceeding that found within protein-coding exons. These elements, collectively referred to as conserved non-coding elements (CNEs) ..." [[User:Genome42|Genome42]] ([[User talk:Genome42|talk]]) 19:51, 27 July 2025 (UTC)
:::::Sounds like a great start, ultraconserved non-coding regions being one potential section. Perhaps the sources provided by Mark Viking may reveal another section that's appropriate for the article, but time will need to be spent to review the information — [[User:VolatileAnomaly|<b style="background-color:black;border:3px solid gray;padding:3px;color:lime;">🪫Volatile</b>]] <sup>[[User talk:VolatileAnomaly|''' 📲T''']] | [[Special:Contributions/VolatileAnomaly|'''⌨️C''']]</sup> 22:24, 27 July 2025 (UTC)
::::::You aren't being very clear. Are you suggesting that we keep the information on Introns, Untranslated regions, Transposable elements, Pseudogenes, etc. but simply expand the section on ultraconserved sequences?
::::::Or are you suggesting a separate article on CNE's (ultraconserved elements)?
::::::If there's strong objection to blanking this article on conserved non-coding sequence then should we add sections on the really important conserved non-coding DNA such as: centromeres, telomeres, SARs, non-coding genes, regulatory sequences, and origins of replication? All of those are covered in [[Non-coding DNA]]. [[User:Genome42|Genome42]] ([[User talk:Genome42|talk]]) 14:52, 28 July 2025 (UTC)
::::::Keep in mind that the underlying issue here is the completely arbitrary distinction between coding DNA and non-coding DNA. It's based on the idea that at one time scientists thought that all functional DNA elements were located in coding DNA. That hasn't been true for 60 years.
::::::This is why we have so many papers in the scientific literature proclaiming to have discovered some new functional DNA element in non-coding DNA as though that's a revolutionary thought.
::::::We could just as easily divide the genome into centromeres and non-centromeres and write an article on conserved non-centromeric DNA as if that was something worthwhile. [[User:Genome42|Genome42]] ([[User talk:Genome42|talk]]) 15:07, 28 July 2025 (UTC)
:::::::I'm going off your comment that "there should be an article on CNEs" here. So yes, I'm agreeing that we remove the redundant info on Introns and untranslated regions and expand the section on ultraconserved sequences, with the idea of ultimately improving this article to host comprehensive coverage on CNEs (with a rename if needed). — [[User:VolatileAnomaly|<b style="background-color:black;border:3px solid gray;padding:3px;color:lime;">🪫Volatile</b>]] <sup>[[User talk:VolatileAnomaly|''' 📲T''']] | [[Special:Contributions/VolatileAnomaly|'''⌨️C''']]</sup> 19:00, 28 July 2025 (UTC)
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