Open Notebook Science Challenge: Difference between revisions

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{{Update|date=February 2024}}

The '''Open Notebook Science Challenge''' is an [[Open Notebook Science]] [[Crowdsourcing]] research project<ref name="ONS Challenge">[http://onschallenge.wikispaces.com/]Open Notebook Science Challenge</ref> that allows anyone to contribute to the effort of measuring the solubility of organic compounds in organic solvents and report their findings using open notebook science.

[[Image:PCAChemicalSpace.png|thumb|PCA Chemical Space for Ethanol]]

The challenge began on September 28, 2008<ref name="began">[http://usefulchem.blogspot.com/2008/09/open-notebook-science-challenge.html]The beginning of the Open Notebook Science challenge.</ref> and now involves researchers and their students in at least 4 different countries<ref name="experiments">[http://onschallenge.wikispaces.com/list+of+experiments]List of experiments</ref> and has resulted in the measurement of over 375 solubility measurements<ref name=measurements>[http://oru.edu/cccda/sl/chemspace/cs.php]Solubility of Organic Compounds in Organic Solvents</ref>.

[[Image:DescriptorChemicalSpace.png|thumb|Descriptor Chemical Space for THF: ALOGP vs. MW]]

The '''Open Notebook Science Challenge''' is a [[crowdsourcing]] research project which collects measurements of the non-aqueous solubility of organic compounds and publishes these as [[open data]]; findings are reported in an [[open notebook science]] manner. Although anyone may contribute research data, the competition is only open to post-secondary students in the US and UK.

The challenge in turn forms part of the UsefulChem project, an ongoing [[open notebook science]] effort to synthesize and screen potential new anti-malarial drugs.<ref name="UsefulChem">[http://usefulchem.wikispaces.com/ UsefulChem]</ref> Data from the Solubility Challenge will be used to build predictive computational models of solubility for use in optimising syntheses.<ref name="predictions">[http://rguha.wordpress.com/2009/01/14/ons-solubility-predictions/ ONS solubility modeling and prediction]</ref>

The challenge began on September 28, 2008<ref name="began">[httphttps://usefulchem.blogspot.com/2008/09/open-notebook-science-challenge.html] The beginning of the Open Notebook Science challenge.]</ref> and, nowas of February 2014, involves researchers and their students infrom at least 4 different countriesinstitutions<ref name="experiments">[http://onschallenge.wikispaces.com/list+of+experiments] List of experiments]</ref> and has resulted in the measurementacquisition of over 3757672 solubility measurements.<ref name=measurements>[http://lxsrv7.oru.edu/cccda~alang/slonsc/chemspace/cs.php] Solubility of Organic Compounds in Organic Solvents]</ref>.

== Prizes ==

To encourage participation, each month an award<ref name="award">[http://www.oru.edu/news/view_news.php?id=1010 A News Story Discussing the Awards]</ref> is given to the student who does, in the opinion of the judges,<ref name="judges">[http://onschallenge.wikispaces.com/judges] ONS Challenge judges]</ref>, the best work. In order to participate, students have to be a US or UK resident.<ref name="rules">[http://onschallenge.wikispaces.com/submetaawards08] ONS Challenge Rules]</ref>. The award is a US$500 cash prize. andThe first three winners also received a year's subscription to the journal ''[[Nature (journal)|Nature]]''. The awards are sponsored by [[Submeta]]<ref name="submeta">[http://www.submeta.org/index.html submeta]</ref> and ''Nature''.

== ChemicalRequest Donationsan experiment ==

As well as concentrating on compounds related to the [[Ugi reaction]], the ONSchallenge allows anyone to request a solubility measurement experiment.<ref name="request">[lxsrv7.oru.edu/~alang/onsc/solubility/solubility.php request a solubility measurement experiment]</ref>

[[Sigma Aldrich]] is also an official sponsor of the Open Notebook Science challenge. Sigma Aldrich is participating by donating and shipping requested chemicals to any experimenters in the US or UK<ref ="Sigma">[http://usefulchem.blogspot.com/2009/02/sigma-aldrich-ships-ons-solubility.html]Sigma Aldrich's involvement with the ONS challenge</ref> for free.

== Chemical donations ==

[[Sigma Aldrich]] is also an official sponsor of the Open Notebook Science challengeChallenge. Sigma Aldrich is participating by donating and shipping requested chemicals to any experimenters in the US or UK<ref name="Sigma">[httphttps://usefulchem.blogspot.com/2009/02/sigma-aldrich-ships-ons-solubility.html] Sigma Aldrich's involvement with the ONS challenge]</ref> for free.

==References==

<references />

[[Category:Open access]]

== External links ==

* [https://web.archive.org/web/20081004212224/http://onschallenge.wikispaces.com/ Open Notebook Science Challenge]

[[Category:Open science]]

[[Category:Open accessdata]]

[[Category:Crowdsourcing]]