Randomized experiment: Difference between revisions

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==Online randomized controlled experiments==

Web sites can run randomized controlled experiments<ref>{{cite book

<ref>{{cite book

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{{main|History of experiments}}

A controlled experiment appears to have been suggested in the Old Testament's [[Book of Daniel]]. King Nebuchadnezzar proposed that some Israelites eat "a daily amount of food and wine from the king's table." Daniel preferred a [[Vegetarian cuisine|vegetarian]] diet, but the official was concerned that the king would "see you looking worse than the other young men your age? The king would then have my head because of you." Daniel then proposed the following controlled experiment: "Test your servants for ten days. Give us nothing but vegetables to eat and water to drink. Then compare our appearance with that of the young men who eat the royal food, and treat your servants in accordance with what you see". ([[Daniel 1, 12– 13]]:12–13).<ref>{{cite journal

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==Empirical evidence that randomization makes a difference==

Empirically differences between randomized and non-randomized studies,<ref>{{cite journal| doi=10.1002/14651858.MR000034.pub2|vauthors=Anglemyer A, Horvath HT, Bero L | title=Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials| journal=Cochrane Database Syst Rev|date=April 2014| pmid=24782322| volume=2014|issue=4 | pages=MR000034| pmc=8191367}}</ref>{{Update inline|reason=Updated version https://www.ncbi.nlm.nih.gov/pubmed/38174786|date = February 2024}} and between adequately and inadequately randomized trials have been difficult to detect.<ref>{{cite journal| doi=10.1002/14651858.MR000012.pub3| vauthors=Odgaard-Jensen J, Vist G, etal |title=Randomisation to protect against selection bias in healthcare trials.| journal=Cochrane Database Syst Rev| date=April 2011| volume=2015 |pmid=21491415|pages=MR000012| issue=4| pmc=7150228}}</ref><ref>{{cite journal| doi=10.1186/1745-6215-15-480|vauthors=Howick J, Mebius A |title=In search of justification for the unpredictability paradox| journal=Trials| year=2014| volume=15| pmid=25490908| pagesarticle-number=480| pmc=4295227 |doi-access=free }}</ref>

== Directed acyclic graph (DAG) explanation of randomization ==