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{{short description|Common human medical data ranges for blood test results}}
{{Reference ranges}}
'''[[Reference range]]sranges (reference intervals) for [[blood test]]stests''' are sets of values used by a [[health professional]] to interpret a set of [[medical test]] results from blood samples. [[Reference rangesrange]]s for [[blood teststest]]s are studied within the field of [[clinical chemistry]] (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the area of [[pathology]] that is generally concerned with analysis of [[bodily fluids]].<ref>{{cite journal |last1=Miri-Dashe |first1=Timzing |last2=Osawe |first2=Sophia |last3=Tokdung |first3=Monday |last4=Daniel |first4=Nenbammun |last5=Choji |first5=Rahila Pam |last6=Mamman |first6=Ille |last7=Deme |first7=Kurt |last8=Damulak |first8=Dapus |last9=Abimiku |first9=Alash'le |title=Comprehensive reference ranges for hematology and clinical chemistry laboratory parameters derived from normal Nigerian adults |journal=PLOS ONE |date=2014 |volume=9 |issue=5 |pages=e93919 |doi=10.1371/journal.pone.0093919 |doi-access=free |pmid=24832127 |pmc=4022493 |bibcode=2014PLoSO...993919M |issn=1932-6203}}</ref><ref>{{cite journal |last1=Lo |first1=Y. C. |last2=Armbruster |first2=David A. |title=Reference Intervals of Common Clinical Chemistry Analytes for Adults in Hong Kong |journal=EJIFCC |date=April 2012 |volume=23 |issue=1 |pages=5–10 |pmid=27683403 |pmc=4975210 |issn=1650-3414}}</ref><ref>{{cite journal |last1=DomBourian |first1=Melkon G. |last2=Helander |first2=Louise |last3=Annen |first3=Kyle |last4=Campbell |first4=Alice |title=Chemistry & Hematology Reference Intervals |journal=Current Diagnosis & Treatment: Pediatrics |date=2025 |url=https://accessmedicine.mhmedical.com/content.aspx?bookid=3480&sectionid=291714492 |publisher=McGraw Hill}}</ref>
 
Blood test results should always be interpreted using the reference range provided by the laboratory that performed the test.<ref>{{cite web|title=Reference Ranges and What They Mean|url=http://labtestsonline.org/understanding/features/ref-ranges/start/6|publisher=Lab Tests Online (USA)|access-date=22 June 2013|archive-date=28 August 2013|archive-url=https://web.archive.org/web/20130828020717/http://labtestsonline.org/understanding/features/ref-ranges/start/6|url-status=dead}}</ref>
 
==Interpretation==
A [[reference range]] is usually defined as the set of values 95 percent of the normal population falls within (that is, 95% [[prediction interval]]).<ref>[{{Cite book |url=https://books.google.com/books?id=Je_pJfb2r0cC&pg=PA19 Page 19] in: {{cite book |author=Stephen K. Bangert MA MB BChir MSc MBA FRCPath; William J. Marshall MA MSc MBBS FRCP FRCPath FRCPEdin FIBiol; Marshall, William Leonard |title=Clinical biochemistry: metabolic and clinical aspects |publisher=Churchill Livingstone/Elsevier |___location=Philadelphia |year=2008 |isbn=978-0-443-10186-1 |editor-last=Bangert |editor-first=Stephen K. |edition=2nd |___location=Philadelphia |page=19 |editor-last2=Marshall |editor-first2=William J.}}</ref> It is determined by collecting data from vast numbers of laboratory tests.<ref>{{citationCite journal |last=Boyd |first=James C. needed|date=AprilJanuary 20222010 |title=Defining laboratory reference values and decision limits: populations, intervals, and interpretations |journal=Asian Journal of Andrology |volume=12 |issue=1 |pages=83–90 |doi=10.1038/aja.2009.9 |issn=1745-7262 |pmc=3739683 |pmid=20111086}}</ref><ref>{{Cite web |title=Reference Ranges & What They Mean |url=https://labtestsonline.org.uk/articles/laboratory-test-reference-ranges |website=Lab Tests Online-UK}}</ref>
 
===Plasma or whole blood===
In this article, all values (except the ones listed below) denote [[blood plasma]] concentration, which is approximately 60–100% larger than the actual blood concentration if the amount inside [[red blood cells]] (RBCs) is negligible. The precise factor depends on [[hematocrit]] as well as amount inside RBCs. Exceptions are mainly those values that denote total blood concentration, and in this article they are:<ref name="pmid33274357">{{citeCite journal| author|vauthors=Bransky A, Larsson A, Aardal E, Ben-Yosef Y, Christenson RH |year=2021 |title=A Novel Approach to Hematology Testing at the Point of Care. | journal=J Appl Lab Med | year= 2021 | volume= 6 | issue= 2 | pages= 532–542 | pmid=33274357 | doi=10.1093/jalm/jfaa186 | pmc=7798949 |pmid=33274357}} </ref>
* All values in ''Hematology – red blood cells'' (except ''hemoglobin in plasma'')
* All values in ''Hematology – white blood cells''
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===Units===
* [[Mass concentration (chemistry)|Mass concentration]] (g/dL or g/L) is the most common measurement unit in the United States. Is usually given with dL (decilitres) as the denominator in the United States, and usually with L (litres) in, for example, Sweden.{{cn|date=February 2024}}
* [[Molar concentration]] (mol/L) is used to a higher degree in most of the rest of the world, including the United Kingdom and other parts of Europe and Australia and New Zealand.<ref>[{{Cite book |last=Dart |first=Richard C. |url=https://books.google.com/books?id=BfdighlyGiwC "Units|title=Medical oftoxicology measurement"]|publisher=Lippincott inWilliams ''Medical& toxicology''Wilkins |year=2004 |isbn=978-0-7817-2845-4 |edition=3, Richardillustrated C.|page=34 Dart|chapter=Units of measurement}}</ref>
* [[International unit]]s (IU) are based on measured [[biological activity]] or effect, or for some substances, a specified equivalent mass.{{cn|date=February 2024}}
Edition: 3, illustrated, Lippincott Williams & Wilkins, 2004, p. 34 {{ISBN|978-0-7817-2845-4}} 1914 pages</ref>
* [[International unit]]s (IU) are based on measured [[biological activity]] or effect, or for some substances, a specified equivalent mass.
* [[Enzyme activity]] ([[katal|kat]]) is commonly used for e.g. [[liver function test]]s like [[Aspartate transaminase|AST]], [[Alanine transaminase|ALT]], [[lactate dehydrogenase|LD]] and [[Gamma-glutamyl transpeptidase|γ-GT]] in Sweden.<ref name=uppsala/>
* [[Percentage]]s and time-dependent units (mol/s) are used for calculated derived parameters, e.g. for [[beta cell]] function in [[Homeostatic model assessment|homeostasis model assessment]] or [[thyroid's secretory capacity]].<ref>{{Cite journal |last=Hill |first=Nathan R. |last2=Levy |first2=Jonathan C. |last3=Matthews |first3=David R. |date=11 July 2013 |title=Expansion of the Homeostasis Model Assessment of β-Cell Function and Insulin Resistance to Enable Clinical Trial Outcome Modeling Through the Interactive Adjustment of Physiology and Treatment Effects: iHOMA2 |url=https://diabetesjournals.org/care/article/36/8/2324/33141/Expansion-of-the-Homeostasis-Model-Assessment-of |journal=Diabetes Care |volume=36 |issue=8 |pages=2324–2330 |doi=10.2337/dc12-0607 |issn=0149-5992 |pmc=3714535 |pmid=23564921}}</ref>
 
===Arterial or venous===
If not otherwise specified, a reference range for a blood test is generally the [[vein|venous]] range, as the standard process of obtaining a sample is by [[venipuncture]]. An exception is for acid–base and [[blood gas]]es, which are generally given for arterial blood.<ref>{{citationCite web needed|datetitle=JulyReference Interval and Critical Results Table |url=https://pathology.vcu.edu/media/pathology/catalog/LAB.GEN.0022CPathologyBloodGasTestingandWholeBloodChemistryRefIntervalsCritValues05.17.2024.pdf |website=VCU Health Pathology |department=Blood Gas 2020Laboratory}}</ref>
 
Still, the blood values are approximately equal between the arterial and venous sides for most substances, with the exception of acid–base, blood gases and drugs (used in [[therapeutic drug monitoring]] (TDM) assays).<ref name="Dufour">[{{Cite magazine |last=Dufour |first=D. Robert |date=April 2000 |title=Arterial versus venous reference ranges |url=http://findarticles.com/p/articles/mi_m3230/is_4_32/ai_61893437/ "Arterial|url-status=dead versus|archive-url=https://web.archive.org/web/20050421011421/http://findarticles.com/p/articles/mi_m3230/is_4_32/ai_61893437/ venous|archive-date=2005-04-21 reference ranges"], ''|magazine=Medical Laboratory Observer'', April, 2000 by D. Robert Dufour}}</ref> Arterial levels for drugs are generally higher than venous levels because of extraction while passing through tissues.<ref name=Dufour/>
 
===Usual or optimal===
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===Variability===
{{Further|Reference range}}
References range may vary with age, sex, race, pregnancy,<ref>{{Cite journal |last=Abbassi-Ghanavati doi|first=M. |last2=Greer 10|first2=L.1097/AOG G.0b013e3181c2bde8| pmid |last3=Cunningham 19935037|first3=F. titleG. |year=2009 |title=Pregnancy and Laboratory Studies| |journal = Obstetrics & Gynecology| |volume =114 114| issue =6 6| pages = 1326–31| year = 2009| last1 doi= Abbassi-Ghanavati | first1 = M10. | last2 = Greer | first2 = L. G1097/AOG.0b013e3181c2bde8 | last3 pmid= Cunningham19935037 | first3 = F. G. | s2cid = 24249021}}</ref> diet, use of prescribed or herbal drugs and stress. Reference ranges often depend on the analytical method used, for reasons such as [[Accuracy and precision|inaccuracy]], lack of [[standardisation]], lack of [[certified reference materials|certified reference material]] and differing [[epitope|antibody reactivity]].<ref>{{citeCite journal |last=Armbruster |first=David |author2last2=Miller |first2=Richard R. |date=August 2007 |title=The Joint Committee for Traceability in Laboratory Medicine (JCTLM): A Global Approach to Promote the Standardisation of Clinical Laboratory Test Results |journal=The Clinical Biochemist Reviews|date=August 2007|volume=28 |issue=3 |pages=105–14 |pmc=1994110 |pmid=17909615}}</ref> Also, reference ranges may be inaccurate when the reference groups used to establish the ranges are small.<ref>{{citeCite journal |titlelast=SampleMeeker Sizes for Prediction Intervals|authorfirst=William Q. Meeker &|last2=Hahn |first2=Gerald J. Hahn|doiyear=10.1080/00224065.1982.11978821 |title=Sample Sizes for Prediction Intervals |journal=Journal of Quality Technology |volume=14|year=1982 |issue=4 |pages=201–206 |doi=10.1080/00224065.1982.11978821}}</ref>
 
==Sorted by concentration==
 
<div class="noprint">
 
===By mass and molarity===
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{{Blood Values}}
 
Hormones predominate at the left part of the scale, shown with a red at ng/L or pmol/L, being in very low concentration. There appears to be the greatest cluster of substances in the yellow part (μg/L or nmol/L), becoming sparser in the green part (mg/L or μmol/L). However, there is another cluster containing many metabolic substances like cholesterol and glucose at the limit with the blue part (g/L or mmol/L).{{cn|date=February 2024}}
 
The unit conversions of substance concentrations from the molar to the mass concentration scale above are made as follows:
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* Measured directly in distance on the scales:
:<math>\log_{10} \frac{\text{molar mass}}{1000} = \text{distance to right (decades)} </math>,
where distance is the direct (not logarithmic) distance in number of [[Decade (log scale)|decades]] or "octaves" to the right the mass concentration is found. To translate from mass to molar concentration, the dividend ([[molar mass]] and the divisor (1000) in the [[Division (mathematics)|division]] change places, or, alternatively, ''distance to right'' is changed to ''distance to left''. Substances with a molar mass around 1000g/mol (e.g. thyroxine) are almost vertically aligned in the mass and molar images. Adrenocorticotropic hormone, on the other hand, with a molar mass of 4540,<ref>[https://www.uniprot.org/uniprot/P01189 PROOPIOMELANOCORTIN; NCBI -->/ POMC] Retrieved on September 28, 2009</ref> is 0.7 decades to the right in the mass image. Substances with molar mass below 1000g/mol (e.g. electrolytes and metabolites) would have "negative" distance, that is, masses deviating to the left.
Many substances given in mass concentration are not given in molar amount because they haven't been added to the article.
 
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|rowspan=2| {{Anchor|Calcium}} Ionized [[calcium]] (Ca) || 1.03,<ref name=Larsson>{{cite journal |vauthors=Larsson L, Ohman S |title=Serum ionized calcium and corrected total calcium in borderline hyperparathyroidism |journal=Clin. Chem. |volume=24 |issue=11 |pages=1962–65 |date=November 1978 |pmid=709830 |doi= 10.1093/clinchem/24.11.1962|url=http://www.clinchem.org/cgi/pmidlookup?view=long&pmid=709830|doi-access=free |url-access=subscription }}</ref> 1.10<ref name=uppsala/> || 1.23,<ref name=Larsson/> 1.30<ref name=uppsala/> || mmol/L ||rowspan=2| See [[hypocalcaemia]] or [[hypercalcaemia]]
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|rowspan=2| {{Anchor|Iron}} Total [[serum iron]] (TSI) – male || 65,<ref name=uimc>{{cite web |author=Slon S |title=Serum Iron |url=http://uimc.discoveryhospital.com/main.php?t=enc&id=1456 |date=2006-09-22 |publisher=University of Illinois Medical Center |access-date=2006-07-06 |url-status=dead |archive-url=https://web.archive.org/web/20061028111833/http://uimc.discoveryhospital.com/main.php?t=enc&id=1456 |archive-date=2006-10-28 }}</ref> 76<ref name=southwest/> || 176,<ref name=uimc/> 198<ref name=southwest/> || µgμg/dL ||rowspan=2| See [[iron deficiency|hypoferremia]] or the following: [[iron overload|iron overload (hemochromatosis)]], [[iron poisoning]], [[siderosis]], [[hemosiderosis]], [[wikt:hyperferremia#Noun|hyperferremia]]
|-
| 11.6,<ref name=DCL>[http://www.dclmexico.com/ingles/hierro_sl.pdf Diagnostic Chemicals Limited > Serum Iron-SL Assay] {{webarchive|url=https://web.archive.org/web/20090106161044/http://www.dclmexico.com/ingles/hierro_sl.pdf |date=2009-01-06 }} July 15, 2005</ref><ref name=mass-iron/> 13.6<ref name=mass-iron/> || 30,<ref name=DCL/> 32,<ref name=mass-iron/> 35<ref name=mass-iron/> || μmol/L
|-
|-
|rowspan=2| Total serum iron (TSI) – female || 26,<ref name=southwest/> 50<ref name=uimc/> || 170<ref name=southwest/><ref name=uimc/> || µgμg/dL ||
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|rowspan=2| Total serum iron (TSI) – [[newborns]] || 100<ref name=uimc/> || 250<ref name=uimc/> || µgμg/dL ||
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| 18<ref name=mass-iron>Derived from mass values using molar mass of 55.85 g•mol−1</ref> || 45<ref name=mass-iron/> || µmolμmol/L ||
|-
|-
|rowspan=2| Total serum iron (TSI) – [[child]]ren || 50<ref name=uimc/> || 120<ref name=uimc/> || µgμg/dL ||
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|-
| 9<ref name=mass-iron/> || 21<ref name=mass-iron/> || µmolμmol/L ||
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| 43,<ref name=mass-iron/> 47<ref name=mass-iron/> || 81,<ref name=mass-iron/> 85<ref name=mass-iron/>|| µmolμmol/L ||
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| [[Transferrin saturation]] || 20<ref name=uimc/> || 50<ref name=uimc/> || % ||
|-
|rowspan=2| {{Anchor|Ferritin}} [[Ferritin]] – Males and [[postmenopausal]] females || 12<ref name=medline>[https://www.nlm.nihmedlineplus.gov/medlineplus/ency/article/003490.htm Ferritin] by: Mark Levin, MD, Hematologist and Oncologist, Newark, NJ. Review provided by VeriMed Healthcare Network</ref> || 300<ref name=medline/><ref name=medscape-ferritin>{{cite web|url=http://emedicine.medscape.com/article/177216-workup#c8|title=Hemochromatosis Workup|author=Andrea Duchini|website=[[Medscape]]|access-date=2016-07-14}} Updated: Jan 02, 2016</ref> || ng/mL or µgμg/L ||
|-
| 27<ref name=mass-ferritin>Derived from mass values using molar mass of 450,000 g•mol−1</ref> || 670<ref name=mass-ferritin/>|| pmol/L ||
|-
|-
|rowspan=2| Ferritin – premenopausal females || 12<ref name=medline/> || 150<ref name=medline/> – 200<ref name=medscape-ferritin/> || ng/mL or µgμg/L ||
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| 27<ref name=mass-ferritin/> || 330<ref name=mass-ferritin/> – 440<ref name=mass-ferritin/> || pmol/L ||
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|rowspan=2| {{Anchor|Ammonia}} [[Ammonia]] || 10,<ref name=mitchell>{{cite journal |vauthors=Mitchell ML, Filippone MD, Wozniak TF |title=Metastatic carcinomatous cirrhosis and hepatic hemosiderosis in a patient heterozygous for the H63D genotype |journal=Arch. Pathol. Lab. Med. |volume=125 |issue=8 |pages=1084–87 |date=August 2001 |pmid=11473464 |doi= 10.5858/2001-125-1084-MCCAHH|url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=125&page=1084 |url-access=subscription }}</ref> 20<ref name=diaz>{{cite journal |vauthors=Diaz J, Tornel PL, Martinez P |title=Reference intervals for blood ammonia in healthy subjects, determined by microdiffusion |journal=Clin. Chem. |volume=41 |issue=7 |page=1048 |date=July 1995 |pmid=7600690 |doi= 10.1093/clinchem/41.7.1048a|doi-access=free }}</ref> || 35,<ref name=mitchell/> 65<ref name=diaz/> || μmol/L ||rowspan=2| See [[wikt:hypoammonemia#Noun|hypoammonemia]] and [[hyperammonemia]]
|-
| 17,<ref name=ammonia-molar>Derived from molar values using molar mass of 17.03 g/mol</ref> 34<ref name=ammonia-molar/> || 60,<ref name=ammonia-molar/> 110<ref name=ammonia-molar/> || μg/dL
|-
|rowspan=2| {{Anchor|Copper}} [[Copper]] (Cu) || 70<ref name=bloodbook/> || 150<ref name=bloodbook/> || µgμg/dL ||rowspan=2| See [[copper deficiency|hypocupremia]] or [[copper toxicity|hypercupremia]]
|-
| 11<ref name=copper-mass>Derived from mass values using molar mass of 63.55 g•mol−1</ref><ref>{{Cite GPnotebook|1040580630|Reference range for copper}}</ref> || 24<ref name=copper-mass/> || μmol/L
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|rowspan=2| {{Anchor|Zinc}} [[Zinc]] (Zn) || 60,<ref name=dlolab>{{cite web |url=http://www.dlolab.com/PDFs/DLO-OCTOBER-2008-LAB-UPDATE.pdf |title=Archived copy |access-date=2010-01-17 |url-status=dead |archive-url=https://web.archive.org/web/20100307231954/http://www.dlolab.com/PDFs/DLO-OCTOBER-2008-LAB-UPDATE.pdf |archive-date=2010-03-07 }}</ref> 72<ref name=zinc-molar>Derived from molar values using molar mass of 65.38 g/mol</ref> || 110,<ref name=zinc-molar/> 130<ref name=dlolab/> || μg/dL ||rowspan=2| See [[zinc deficiency]] or [[zinc#Poisoning|zinc poisoning]]
|-
| 9.2,<ref name=zinc-mass>Derived from mass values using molar mass of 65.38 g/mol</ref> 11<ref name=uppsala/> || 17,<ref name=uppsala/> 20<ref name=zinc-mass/> || µmolμmol/L
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|rowspan=2| {{Anchor|Magnesium}} [[Magnesium]] || 1.5,<ref name=bloodbook/> 1.7<ref name=magnesium-molar>Derived from molar values using molar mass of 24.31 g/mol</ref> || 2.0,<ref name=bloodbook/> 2.3<ref name=magnesium-molar/> || mEq/L or mg/dL ||rowspan=2| See [[hypomagnesemia]] or [[hypermagnesemia]]
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{{Further|Acid–base homeostasis}}
{{Further|Arterial blood gas test|Arterial blood gas test#Parameters and reference ranges}}
If [[artery|arterial]]/[[vein|venous]] is not specified for an acid–base or blood gas value, then it generally refers to arterial, and not venous which otherwise is standard for other blood tests.{{cn|date=February 2024}}
 
Acid–base and blood gases are among the few blood constituents that exhibit substantial difference between arterial and venous values.<ref name=Dufour/> Still, pH, bicarbonate and base excess show a high level of [[inter-rater reliability|inter-method reliability]] between arterial and venous tests, so arterial and venous values are roughly equivalent for these.<ref name=middleton>{{cite journal |vauthors=Middleton P, Kelly AM, Brown J, Robertson M |title=Agreements between arterial and central venous values for pH, bicarbonate, base excess, and lactate |journal=Emerg Med J |volume=23 |issue=8 |pages=622–24 |date=August 2006 |pmid=16858095 |pmc=2564165 |doi=10.1136/emj.2006.035915 }}</ref>
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|rowspan=2| [[pH]] || Arterial || 7.34,<ref name=southwest/> 7.35<ref name=firstaid/> || 7.44,<ref name=southwest/> 7.45<ref name=firstaid/> ||
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| Venous || 7.31<ref name=brookside>[http://www.brooksidepress.org/Products/OperationalMedicine/DATA/operationalmed/Lab/ABG_ArterialBloodGas.htm The Medical Education Division of the Brookside Associates--> / ABG (Arterial Blood Gas)] Retrieved on Dec 6, 2009</ref> || 7.41<ref name=brookside/> ||
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|rowspan=3| [[Alanine transaminase]] (ALT/ALAT<ref name=uppsala/>) || || 5,<ref name=Nohring/> 7,<ref name=southwest/> 8<ref name=firstaid>Last page of {{cite book |author1=Deepak A. Rao |author2=Le, Tao |author3=Bhushan, Vikas |title=First Aid for the USMLE Step 1 2008 (First Aid for the Usmle Step 1) |publisher=McGraw-Hill Medical |year=2007 |isbn=978-0-07-149868-5 |url-access=registration |url=https://archive.org/details/firstaidforusmle00taol }}</ref> || 20,<ref name=firstaid/> 21,<ref name=merck/> 56<ref name=southwest/> || U/L ||rowspan=3| Also called ''serum glutamic pyruvic transaminase'' (SGPT)
|-
| Female || 0.15<ref name=uppsala/> || 0.75<ref name=uppsala/> ||rowspan=2| µμ[[katal|kat]]/L
|-
| Male || 0.15<ref name=uppsala/> || 1.1<ref name=uppsala/>
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|rowspan=4| [[Aspartate transaminase]] (AST/ASAT<ref name=uppsala/>) ||rowspan=2| Female || 6<ref name=gpnotebook-ast>[http://www.gpnotebook.co.uk/simplepage.cfm?ID=322240579 GPnotebook > reference range (AST)] {{Webarchive|url=https://web.archive.org/web/20170107125542/http://www.gpnotebook.co.uk/simplepage.cfm?ID=322240579 |date=2017-01-07 }} Retrieved on Dec 7, 2009</ref> || 34<ref name=gpnotebook-ast/> || IU/L ||rowspan=4| Also called <br /> ''serum glutamic oxaloacetic transaminase'' (SGOT)
|-
| 0.25<ref name=uppsala/> || 0.60<ref name=uppsala/> || µμ[[katal|kat]]/L
|-
|rowspan=2| Male || 8<ref name=gpnotebook-ast/> || 40<ref name=gpnotebook-ast/> || IU/L
|-
| 0.25<ref name=uppsala/> || 0.75<ref name=uppsala/> || µμ[[katal|kat]]/L
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|rowspan=3| [[Alkaline phosphatase]] (ALP) || || 0.6<ref name=uppsala/> || 1.8<ref name=uppsala/> || µμ[[katal|kat]]/L ||
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| Female || 42<ref name=Nohring>Fachwörterbuch Kompakt Medizin E-D/D-E. Author: Fritz-Jürgen Nöhring. Edition 2. Publisher:Elsevier, Urban&FischerVerlag, 2004. {{ISBN|978-3-437-15120-0}}. Length: 1288 pages</ref> || 98<ref name=Nohring/> ||rowspan=2| U/L ||
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|rowspan=3| [[Gamma glutamyl transferase]] (GGT) || || 5,<ref name=Nohring/> 8<ref name=southwest/> || 40,<ref name=Nohring/> 78<ref name=southwest/> || U/L ||
|-
| Female || || 0.63<ref name="MDI">{{cite web|url=http://www.mdi-labor.de/l_leistungsverzeichnis_detail.php?u_id=663&init=letter |title=Gamma-GT |work=Leistungsverzeichnis |publisher=Medizinisch-Diagnostische Institute |access-date=20 November 2011 |url-status=dead |archive-url=https://web.archive.org/web/20120425233448/http://www.mdi-labor.de/l_leistungsverzeichnis_detail.php?u_id=663&init=letter |archive-date=25 April 2012 }}</ref> || µμ[[katal|kat]]/L ||
|-
| Male || || 0.92<ref name="MDI" /> || µμ[[katal|kat]]/L ||
|-
|}
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|rowspan=4| [[Creatine kinase]] (CK) ||rowspan=2| Male || 24,<ref name="GPnotebook_1436155929">{{Cite GPnotebook|1436155929|Creatine kinase}}</ref> 38,<ref name=southwest/> 60<ref name=Nohring/> || 174,<ref name=bloodbook/> 320<ref name=Nohring/> || U/L or ng/mL ||
|-
| 0.42<ref name=Lee2009p585>[https://books.google.com/books?id=AUSIRcV_as0C&pg=PA585 Page 585] in: {{cite book |author=Lee, Mary Ann |title=Basic Skills in Interpreting Laboratory Data |publisher=Amer Soc of Health System |year=2009 |isbn=978-1-58528-180-0 }}</ref> || 1.5<ref name=Lee2009p585/> || µkatμkat/L ||
|-
| rowspan=2| Female || 24,<ref name="GPnotebook_1436155929"/> 38,<ref name=southwest/> 96<ref name=bloodbook/> || 140,<ref name=bloodbook/> 200<ref name=Nohring/> || U/L or ng/mL ||
|-
| 0.17<ref name=Lee2009p585/> || 1.17<ref name=Lee2009p585/> || µkatμkat/L ||
|-
| [[CK-MB]] || || 0 || 3,<ref name=southwest/> 3.8,<ref name=uppsala/> 5<ref name=Nohring/> || ng/mL or μg/L<ref name=uppsala/> ||
|-
|rowspan=2| [[Myoglobin]] || Female || 1<ref name=MediaLab>[http://www.medialabinc.net/muscle-keyword.aspx Muscle Information and Courses from MediaLab, Inc. > Cardiac Biomarkers] Retrieved on April 22, 2010</ref> || 66<ref name=MediaLab/> ||rowspan=2| ng/mL or µgμg/L ||
|-
| Male || 17<ref name=MediaLab/> || 106<ref name=MediaLab/> ||
Line 354 ⟶ 351:
|not established
|
|more than adults <ref>{{Cite journal|date=2016-07-01|title=Plasma cardiac troponin I concentrations in healthy neonates, children and adolescents measured with a high sensitive immunoassay method: High sensitive troponin I in pediatric age|url=https://www.sciencedirect.com/science/article/abs/pii/S0009898116301553|journal=Clinica Chimica Acta|language=en|volume=458|pages=68–71|doi=10.1016/j.cca.2016.04.029|pmid=27118089|issn=0009-8981|last1=Caselli|first1=C.|last2=Cangemi|first2=G.|last3=Masotti|first3=S.|last4=Ragusa|first4=R.|last5=Gennai|first5=I.|last6=Del Ry|first6=S.|last7=Prontera|first7=C.|last8=Clerico|first8=A.|url-access=subscription}}</ref><ref>{{Cite journal|last1=Baum|first1=Hannsjörg|last2=Hinze|first2=Anika|last3=Bartels|first3=Peter|last4=Neumeier|first4=Dieter|date=2004-12-01|title=Reference values for cardiac troponins T and I in healthy neonates|url=https://www.sciencedirect.com/science/article/pii/S0009912004002218|journal=Clinical Biochemistry|language=en|volume=37|issue=12|pages=1079–82|doi=10.1016/j.clinbiochem.2004.08.003|pmid=15589813|issn=0009-9120|url-access=subscription}}</ref>
|}
 
Line 431 ⟶ 428:
! Comments
|-
| [[Alpha fetoprotein]] (AFP) || || 44<ref name=southwest/> || ng/mL or µgμg/L || Hepatocellular carcinoma or testicular cancer
|-
| Beta [[human chorionic gonadotrophin]] (β-hCG) || In males and non-pregnant females || 5<ref name=southwest/> || IU/L or mU/mL || choriocarcinoma
Line 437 ⟶ 434:
| [[CA19-9]] || || 40<ref name=southwest/> || U/mL || Pancreatic cancer
|-
| [[CA-125]] || || 30,<ref name=gp-ca125>[http://www.gpnotebook.co.uk/simplepage.cfm?ID=-100270014 GP Notebook > range (reference, ca-125)] Retrieved on Jan 5, 2009</ref> 35<ref>[http://www.clinlabnavigator.com/Test-Interpretations/ca-125.html ClinLab Navigator > Test Interpretations > CA-125] {{Webarchive|url=https://web.archive.org/web/20120626000109/http://www.clinlabnavigator.com/Test-Interpretations/ca-125.html |date=2012-06-26 }} Retrieved on March 8, 2011</ref> || kU/L or U/mL ||
|-
|rowspan=3| [[Carcinoembryonic antigen]] (CEA) || Non-smokers, 50 years || 3.4,<ref name=uppsala/> 3.6<ref name=bjerner>{{cite journal |vauthors=Bjerner J, Høgetveit A, Wold Akselberg K, etal |s2cid=12545738 |title=Reference intervals for carcinoembryonic antigen (CEA), CA125, MUC1, Alfa-foeto-protein (AFP), neuron-specific enolase (NSE) and CA19.9 from the NORIP study |journal=Scandinavian Journal of Clinical and Laboratory Investigation |volume= 68|issue= 8|pages=703–13 |date=June 2008 |pmid=18609108 |doi=10.1080/00365510802126836 |url=https://figshare.com/articles/journal_contribution/11808120 }}</ref> ||rowspan=3| μg/L ||
Line 527 ⟶ 524:
|rowspan=8| [[Testosterone]] ||rowspan=2| Male, overall || 8,<ref name=AA>{{Cite web|url=http://www.andrologyaustralia.org/pageContent.asp?pageCode=LOWTESTDIAG#LOWTESTDIAGNORM|title=Andrology Australia: Your Health > Low Testosterone > Diagnosis|access-date=2008-11-28|archive-date=2012-02-17|archive-url=https://web.archive.org/web/20120217051046/http://www.andrologyaustralia.org/pageContent.asp?pageCode=LOWTESTDIAG#LOWTESTDIAGNORM|url-status=dead}}</ref> 10<ref name=testosterone-mass>Derived from mass values using molar mass of 288.42g/mol</ref> || 27,<ref name=AA/> 35<ref name=testosterone-mass/> || nmol/L
|-
| 230,<ref name=testosterone-molar>Derived from molar values using molar mass of 288.42g/mol</ref> 300<ref name=medline-testosterone>[https://www.nlm.nihmedlineplus.gov/medlineplus/ency/article/003707.htm#Normal%20Values MedlinePlus > Testosterone] Update Date: 3/18/2008. Updated by: Elizabeth H. Holt, MD, PhD, Yale University. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director</ref> || 780–1000<ref name=testosterone-molar/><ref name=medline-testosterone/> || ng/dL
|-
|rowspan=2| Male < 50 years || 10<ref name=uppsala/> || 45<ref name=uppsala/> || nmol/L
Line 543 ⟶ 540:
|rowspan=4| [[17α-Hydroxyprogesterone]] ||rowspan=2| male || 0.06<ref name=bloodbook/> || 3.0<ref name=bloodbook/> || mg/L
|-
| 0.18<ref name=17hpg-mass>Derived from mass values using molar mass of 330.46g/mol</ref> || 9.1<ref name=17hpg-mass/> || µmolμmol/L
|-
|rowspan=2| Female (Follicular phase) || 0.2<ref name=bloodbook/> || 1.0<ref name=bloodbook/> || mg/L
|-
| 0.6<ref name=17hpg-mass/> || 3.0<ref name=17hpg-mass/> || µmolμmol/L
|-
|rowspan=6| [[Follicle-stimulating hormone|Follicle-stimulating<br /> hormone]] (FSH)<br />{{hatnote|-more detailed menstrual cycle<br /> ranges in [[:File:Follicle-stimulating hormone (FSH) during menstrual cycle.png|separate diagram]]}} || Prepubertal || <1<ref name=gpnotebook-FSH>[http://www.gpnotebook.co.uk/simplepage.cfm?ID=436600899 reference range (FSH)] GPnotebook. Retrieved on September 27, 2009</ref> || 3<ref name=gpnotebook-FSH/> ||rowspan=6| IU/L
Line 586 ⟶ 583:
|rowspan=2| [[Progesterone]]<br />{{hatnote|-more detailed ranges<br /> in [[Progesterone#Levels|Progesterone]] article}} ||rowspan=2| Female in mid-[[luteal phase]] (day 21–23) || 17,<ref name=Stricker/> 35<ref name=progesterone-mass>Derived from mass values using molar mass of 314.46 g/mol</ref> || 92<ref name="progesterone-mass"/> || nmol/L
|-
| 6,<ref name=Stricker/> 11<ref name=Bhattacharya>Bhattacharya Sudhindra Mohan (July/August 2005) [http://medind.nic.in/jaq/t05/i4/jaqt05i4p350.pdf Mid-luteal phase plasma progesterone levels in spontaneous and clomiphene citrate induced conception cycles] {{Webarchive|url=https://web.archive.org/web/20100602092012/http://medind.nic.in/jaq/t05/i4/jaqt05i4p350.pdf |date=2010-06-02 }} J Obstet Gynecol India Vol. 55, No. 4 : July/August 2005 pp. 350–52</ref> || 29<ref name=Bhattacharya/> || ng/mL
|-
|rowspan=3| [[Androstenedione]] || Adult male and female || 60<ref name=nyhq/> || 270<ref name=nyhq/> ||rowspan=3| ng/dL
Line 594 ⟶ 591:
| Prepubertal || || < 60<ref name=nyhq/>
|-
| [[Dehydroepiandrosterone sulfate]] {{hatnote|-more detailed ranges<br /> in [[Dehydroepiandrosterone sulfate|DHEA-S]] article}} || Adult male and female || 30<ref name=mayo>[http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/8493 Dehydroepiandrosterone Sulfate (DHEA-S), Serum] {{Webarchive|url=https://web.archive.org/web/20180314080932/https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/8493 |date=2018-03-14 }} at Mayo Foundation For Medical Education And Research. Retrieved July 2012</ref> || 400<ref name=mayo/> || µgμg/dL
|-
|rowspan=2| [[Sex hormone-binding globulin|SHBG]] <br />{{hatnote|-more detailed ranges<br /> in [[Sex hormone-binding globulin#Blood values|SHBG]] article}} || Adult female || 40<ref name=mayo-shbg>[http://www.mayomedicallaboratories.com/test-catalog/print.php?unit_code=91215 Unit Code 91215] {{webarchive|url=https://web.archive.org/web/20110720111631/http://www.mayomedicallaboratories.com/test-catalog/print.php?unit_code=91215 |date=2011-07-20 }} at [[Mayo Clinic]] Medical Laboratories. Retrieved April 2011</ref> || 120<ref name=mayo-shbg/> ||rowspan=2| nmol/L
Line 616 ⟶ 613:
! Unit
|-
|rowspan=2| [[Adrenocorticotropic hormone]] (ACTH) ||rowspan=2| || 2.2<ref name="Nieman">{{cite web |last1=Nieman |first1=Lynnette K |title=Measurement of ACTH, CRH, and other hypothalamic and pituitary peptides |url=https://www.uptodate.com/contents/measurement-of-acth-crh-and-other-hypothalamic-and-pituitary-peptides |website=www.uptodate.com |publisher=UpToDate |access-date=25 June 2021 |date=29 September 2019 |archive-date=25 June 2021 |archive-url=https://web.archive.org/web/20210625125528/https://www.uptodate.com/contents/measurement-of-acth-crh-and-other-hypothalamic-and-pituitary-peptides |url-status=dead }}</ref> || 13.3<ref name="Nieman"/> || pmol/L
|-
| 20<ref name=southwest/> || 100<ref name=southwest/> || pg/mL
|-
|rowspan=4| [[Cortisol]] ||rowspan=2| 09:00 [[ante meridiem|am]] || 140<ref name=goodhope>[http://www.goodhope.org.uk/departments/pathweb/refranges.htm Biochemistry Reference Ranges at Good Hope Hospital] {{Webarchive|url=https://web.archive.org/web/20100720014644/http://www.goodhope.org.uk/Departments/pathweb/refranges.htm |date=2010-07-20 }} Retrieved on Nov 8, 2009</ref> || 700<ref name=goodhope/> || nmol/L
|-
| 5<ref name=cortisol-derived>Derived from molar values using molar mass of 362 g/mol</ref> || 25<ref name=cortisol-derived/> || μg/dL
Line 642 ⟶ 639:
|rowspan=4| [[Prolactin]]<br /> {{hatnote|-more detailed ranges in<br /> [[Prolactin]] article}} ||rowspan=2| Female || 71,<ref name=Beltran_2008/> 105<ref name=Beltran_2008/> || 348,<ref name=Beltran_2008/> 548<ref name=Beltran_2008>Taken from the assay method giving the lowest and highest estimate, respectively, from [http://www.clinchem.org/cgi/content/full/54/10/1673/T2 Table 2] in: {{cite journal |vauthors=Beltran L, Fahie-Wilson MN, McKenna TJ, Kavanagh L, Smith TP |title=Serum total prolactin and monomeric prolactin reference intervals determined by precipitation with polyethylene glycol: evaluation and validation on common immunoassay platforms |journal=Clinical Chemistry |volume=54 |issue=10 |pages=1673–81 |date=October 2008 |pmid=18719199 |doi=10.1373/clinchem.2008.105312|doi-access=free }}</ref> || mIU/L
|-
| 3.4,<ref name=Beltran_2008/> 3.9<ref name=Beltran_2008/> || 16.4,<ref name=Beltran_2008/> 20.3<ref name=Beltran_2008/> || µgμg/L
|-
|rowspan=2| Male || 58,<ref name=Beltran_2008/> 89<ref name=Beltran_2008/> || 277,<ref name=Beltran_2008/> 365<ref name=Beltran_2008/> || mIU/L
|-
| 2.7,<ref name=Beltran_2008/> 3.3<ref name=Beltran_2008/> || 13.0,<ref name=Beltran_2008/> 13.5<ref name=Beltran_2008/> || µgμg/L
|-
|rowspan=2| [[Parathyroid hormone]] (PTH) || || 10,<ref name=pth-molar>Derived from molar values using molar mass of 9.4 kDa</ref> 17<ref name=Aloia>[https://www.ncbi.nlm.nih.gov/pmc/articles/mid/NIHMS10653/table/T2/ Table 2] in: {{cite journal |vauthors=Aloia JF, Feuerman M, Yeh JK |title=Reference range for serum parathyroid hormone |journal=Endocr Pract |volume=12 |issue=2 |pages=137–44 |year=2006 |pmid=16690460 |pmc=1482827 |doi= 10.4158/ep.12.2.137}}</ref> || 65,<ref name=pth-molar/> 70<ref name=Aloia/> || pg/mL
Line 674 ⟶ 671:
|rowspan=2| [[Aldosterone-to-renin ratio]] <br />{{hatnote|-more detailed ranges in <br />[[Aldosterone-to-renin ratio|Aldosterone/renin ratio]] article}} ||rowspan=2| Adult || || 13.1,<ref name=Tiu2004/> 35.0<ref name=Tiu2004>{{cite journal |vauthors=Tiu SC, Choi CH, Shek CC, etal |title=The use of aldosterone-renin ratio as a diagnostic test for primary hyperaldosteronism and its test characteristics under different conditions of blood sampling |journal=The Journal of Clinical Endocrinology and Metabolism |volume=90 |issue=1 |pages=72–78 |date=January 2005 |pmid=15483077 |doi=10.1210/jc.2004-1149|citeseerx=10.1.1.117.5182 }}</ref> || ng/dL per ng/(mL·h)
|-
| || 360,<ref name=Tiu2004/> 970<ref name=Tiu2004/> || pmol/liter per µgμg/(L·h)
|}
 
Line 691 ⟶ 688:
! Upper limit
|-
| [[Vitamin A]] || || 30<ref name=bloodbook/> || 65<ref name=bloodbook/> || || || µgμg/dL
|-
|rowspan=2| [[Vitamin B9|Vitamin B<sub>9</sub>]] <br /> (Folic acid/Folate) – '''Serum''' ||rowspan=2| Age > 1 year || 3.0<ref name=cmft>[http://www.cmft.nhs.uk/directorates/labmedicine/USERGUIDE/pdfs/Haem%20-%20Coagulation%20Ref%20Ranges.pdf Central Manchester University Hospitals -->/ Reference ranges] {{Webarchive|url=https://web.archive.org/web/20121130102124/http://www.cmft.nhs.uk/directorates/labmedicine/USERGUIDE/pdfs/Haem%20-%20Coagulation%20Ref%20Ranges.pdf |date=2012-11-30 }} Retrieved on July 9, 2009</ref> || 16<ref name=cmft/> || 5<ref name=Chandler>[http://www.hosp.uky.edu/Clinlab/report.pdf University of Kentucky Chandler Medical Center > Clinical Lab Reference Range Guide] Retrieved on April 28, 2009</ref> || || ng/mL or μg/L
|-
| 6.8<ref name=b9-mass>Derived from mass values using molar mass of 441 mol−1</ref> || 36<ref name=b9-mass/> || 11<ref name=b9-mass/> || || nmol/L
Line 727 ⟶ 724:
|}
 
===ToxinsToxic Substances===
{| class="wikitable"
! Test
Line 734 ⟶ 731:
! Unit
|-
| [[Lead]] || [[Optimal health range]] || < 20<ref name=merck/> or 40<ref name=bloodbook/> || µgμg/dL
|-
|rowspan=2| [[Blood ethanol content]] ||rowspan=2| Limit for [[Driving under the influence|drunk driving]] || 0,<ref name=drunk-driving/> 0.2,<ref name=drunk-driving>For [[Driving under the influence]] by country, see [[Drunk driving law by country]]</ref> 0.8<ref name=drunk-driving/> || [[Per mil|‰]] or g/L
Line 889 ⟶ 886:
! Comments
|-
| Thrombocyte/[[Platelets|Platelet]] count (Plt)|| 140,<ref name=southwest/> 150<ref name=uppsala/><ref name=firstaid/> || 350,<ref name=uppsala/><ref name=bloodbook/> 400,<ref name=firstaid/> 450<ref name=southwest/> || x10<sup>9</sup>/L or<br /> x1000/µLμL ||
|-
| [[Mean platelet volume]] (MPV) || 7.2,<ref name=Demirin2011>{{cite journal |vauthors=Demirin H, Ozhan H, Ucgun T, Celer A, Bulur S, Cil H, Gunes C, Yildirim HA |title=Normal range of mean platelet volume in healthy subjects: Insight from a large epidemiologic study |journal=Thromb. Res. |volume=128 |issue=4 |pages=358–60 |year=2011 |pmid=21620440 |doi=10.1016/j.thromres.2011.05.007 |hdl=20.500.12684/3830 |hdl-access=free }}</ref> 7.4,<ref name=labcareplus>[http://www.labcareplus.org/docs/REFERENCE_RANGES.pdf Normal Values: RBC, Hgb, Hct, Indices, RDW, Platelets, and MPV (Conventional Units)] {{Webarchive|url=https://web.archive.org/web/20110727010934/http://www.labcareplus.org/docs/REFERENCE_RANGES.pdf |date=2011-07-27 }} From labcareplus. Retrieved 4 nov, 2010</ref> 7.5<ref name=Lozano1988>{{cite journal |vauthors=Lozano M, Narváez J, Faúndez A, Mazzara R, Cid J, Jou JM, Marín JL, Ordinas A |title=[Platelet count and mean platelet volume in the Spanish population] |language=es|journal=Med Clin (Barc) |volume=110 |issue=20 |pages=774–77 |year=1998 |pmid=9666418 }}</ref> || 10.4,<ref name=labcareplus/> 11.5,<ref name=Lozano1988/> 11.7<ref name=Demirin2011/> || [[femtolitre|fL]] ||
|-
| [[Prothrombin time]] (PT)|| 10,<ref name=merck/> 11,<ref name=firstaid/><ref name=medline003652>{{MedlinePlusEncyclopedia|003652}}</ref> 12<ref name=southwest/> || 13,<ref name=merck/> 13.5,<ref name=medline003652/> 14,<ref name=southwest/> 15<ref name=firstaid/> || s || PT reference varies between laboratory kits – INR is standardised
Line 905 ⟶ 902:
|rowspan=2| [[Antithrombin]] || 0.80<ref name=uppsala/> || 1.2<ref name=uppsala/> || kIU/L || rowspan=2 |
|-
| 0.15,<ref name=teruya2014>{{EMedicine|article|2084978|Antithrombin III}}</ref> 0.17<ref name=mgh>[http://mghlabtest.partners.org/coagbook/co000300.htm Antithrombin CO000300] {{Webarchive|url=https://web.archive.org/web/20170909215510/http://mghlabtest.partners.org/coagbook/co000300.htm |date=2017-09-09 }} in ''Coagulation Test Handbook'' at [[Massachusetts General Hospital]]. In turn citing:
* Elizabeth M. Van Cott, M.D., and Michael Laposata, M.D., Ph.D., "Coagulation." In: Jacobs DS et al, ed. The Laboratory Test Handbook, 5th Edition. Lexi-Comp, Cleveland, 2001; 327–58.</ref> || 0.2,<ref name=teruya2014/> 0.39<ref name=mgh/> || mg/mL
|-
Line 1,039 ⟶ 1,036:
| 0.4<ref name=Nohring/> || 1.7<ref name=Nohring/> || μmol/L ||
|-
| 1.8<ref name=uppsala/> || 3.4<ref name=uppsala/> || µμ[[katal|kat]]/L || < 70 years old<ref name=uppsala/>
|-
|rowspan=3| [[Amylase]] || 25,<ref name=firstaid/> 30,<ref name=southwest/> 53<ref name=bloodbook/> || 110,<ref name=southwest/> 120,<ref>{{Cite GPnotebook|309002307|Reference range (amylase)}}</ref> 123,<ref name=bloodbook/> 125,<ref name=firstaid/> 190<ref name=Nohring/> || U/L ||
|-
| 0.15<ref name=uppsala/> || 1.1<ref name=uppsala/> || µμ[[katal|kat]]/L ||
|-
| 200<ref name=crp-mass>Derived from mass using molar mass of 25,106 g/mol</ref> || 240<ref name=crp-mass/> || nmol/L ||
Line 1,057 ⟶ 1,054:
| [[Acid phosphatase]] || || 3.0<ref name=Nohring/> || ng/mL ||
|-
| [[Eosinophil cationic protein]] (ECP) || 2.3<ref name=uppsala/> || 16<ref name=uppsala/> || µgμg/L ||
|}
 
Line 1,174 ⟶ 1,171:
|rowspan=2| [[Paracetamol]] || || 30<ref name=rosen>{{cite book|title=Rosen's Emergency Medicine – Concepts and Clinical Practice|author1=John Marx |author2=Ron Walls |author3=Robert Hockberger |publisher=Elsevier Health Sciences|year=2013|isbn=9781455749874}}</ref> || mg/L ||rowspan=2| Risk of [[paracetamol toxicity]] at higher levels
|-
| || 200<ref name=rosen/> || µmolμmol/L
|}