CYP2C8 and Category talk:People from Cook County, Illinois: Difference between pages

Revision as of 23:23, 19 April 2007

Revision as of 04:35, 18 July 2007

Line 1:

{{WikiProject Illinois|class=Category}}

{{protein

|Name=cytochrome P450, family 2, subfamily C, polypeptide 8

|caption=

|image=

|width=

|HGNCid=2622

|Symbol=CYP2C8

|AltSymbols=

|EntrezGene=1558

|OMIM=601129

|RefSeq=NM_000770

|UniProt=P10632

|PDB=

|ECnumber=

|Chromosome=10

|Arm=q

|Band=24.1

|LocusSupplementaryData=

}}

'''Cytochrome P450 2C8''' (abbreviated '''CYP2C8'''), a member of the [[cytochrome P450]] mixed-function oxidase system, is involved in the metabolism of [[xenobiotic]]s in the body.

==CYP2C8 Ligands==

{| border="0" align="center" cellpadding="2" cellspacing="2"

| colspan="2" bgcolor="#CCCCCC" | '''Selected inducers, inhibitors and substrates of CYP2C8¹'''

|-

| width="15%" bgcolor="#CCCCCC" | Type

| width="85%" bgcolor="#CCCCCC" | Agent

|-

| bgcolor="#efefef" | inducers

| bgcolor="#dfefff" | [[rifampicin]]

|-

| bgcolor="#efefef" | inhibitors

| bgcolor="#dfefff" | [[gemfibrozil]], [[glitazone]]s ([[rosiglitazone]], [[pioglitazone]], etc), [[montelukast]], [[quercetin]], [[trimethoprim]]

|-

| bgcolor="#efefef" | substrates

| bgcolor="#dfefff" | [[cerivastatin]], [[paclitaxel]], [[repaglinide]], [[torasemide]]

|-

| colspan="2" bgcolor="#dfefff" | '''Notes:'''

#Where classes of agents are listed, there may be exceptions within the class.

|}

== See also ==

*[[Cytochrome P450 oxidase]]

{{Cytochrome P450}}

[[Category:Cytochrome P450]]