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[[Biliary sepsis]] is a systemic complication of acute cholangitis that occurs when infection spreads from the bile ducts into the bloodstream.
A systemic infection resulting from [[Intestinal permeability|bacterial translocation]] from the [[biliary tract]], most commonly due to acute [[Primary sclerosing cholangitis|cholangitis]] or [[suppurative cholecystiti]]<nowiki/>s. It is a life-threatening complication of biliary obstruction (e.g., [[Common bile duct stone|choledocholithiasis]], strictures) and requires urgent intervention.<ref>{{Cite journal |last=Kiriyama |first=Seiki |last2=Kozaka |first2=Kazuto |last3=Takada |first3=Tadahiro |last4=Strasberg |first4=Steven M. |last5=Pitt |first5=Henry A. |last6=Gabata |first6=Toshifumi |last7=Hata |first7=Jiro |last8=Liau |first8=Kui-Hin |last9=Miura |first9=Fumihiko |last10=Horiguchi |first10=Akihiko |last11=Liu |first11=Keng-Hao |last12=Su |first12=Cheng-Hsi |last13=Wada |first13=Keita |last14=Jagannath |first14=Palepu |last15=Itoi |first15=Takao |date=2018 |title=Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholangitis (with videos) |url=https://onlinelibrary.wiley.com/doi/abs/10.1002/jhbp.512 |journal=Journal of Hepato-Biliary-Pancreatic Sciences |language=en |volume=25 |issue=1 |pages=17–30 |doi=10.1002/jhbp.512 |issn=1868-6982|url-access=subscription }}</ref>
==Prognosis==
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