Wikipedia:WikiProject Molecular Biology/Molecular and Cell Biology: Difference between revisions

Content deleted Content added
m Reverted edits by Engarrafamento (talk): unexplained content removal (HG) (3.4.13)
 
(293 intermediate revisions by 100 users not shown)
Line 1:
{{short description|Sub-project of WikiProject Molecular Biology}}
Some [[Wikipedian]]s have formed a [[Wikipedia:WikiProject|project]] to better organize information in articles related to '''Molecular and Cellular Biology'''. This page and its subpages contain their suggestions; it is hoped that this project will help to focus the efforts of other Wikipedians. If you would like to help, please inquire on the [[{{NAMESPACE}} talk:{{PAGENAME}}|talk page]] and see the [[Wikipedia:to-do list|to-do list]] there.
{{MolBioHeader/Taskforce
 
|about =
For more information on WikiProjects, please see [[Wikipedia:WikiProjects]] and [[Wikipedia:WikiProject best practices]].
===Scope===
[[Image:Calvin-cycle2.png|thumb|right|400px|'''Featured Molecular and Cellular Biology Illustration'''. Image:Calvin-cycle2.png by [[User:Adenosine]]]]
This [[WP:WikiProject|project]] aims to improve and organise articles related to [[Molecular biology|molecular]] and [[Cell biology|cell biology]] on Wikipedia. If you would like to help, feel free to add yourself to the [[WP:WikiProject Molecular and Cell Biology/Participants|list of participants]], drop by our [[WT:MCB|discussion page]] or just look over the [[#How you can help the project|How you can help]] section below.
==Title==
'''WikiProject on Molecular and Cellular Biology'''
 
==Scope=Goals===
Collect and organize the wealth of information in [[Biological database|databases]] and academic journals on genomes, proteomes and biological functions to ensure that it is accessible to both researchers and laypeople <br/>
<!-- The SCOPE of your project is its most important attribute.
Improve articles to [https://tools.wmflabs.org/enwp10/cgi-bin/list2.fcgi?run=yes&projecta=MCB&quality=FA-Class featured article] status, especially [[WP:Vital_articles#Science_.28192_articles.29|vital articles]], with a particular focus on subjects that are discussed at the primary and secondary school level <br/>
This is where you tell people *precisely* what is is you are doing and why.
Create a standard system for presenting the information about the proteins and cells that are discussed in Wikipedia articles
This is where BOLDNESS is proven. -->
This project aims to improve coverage of [[Molecular biology|molecular]] and [[Cell biology|cell biology]] at wikipedia. A major problem facing biology is organizing the vast amount of information that has been and continues to be collected about genomes, proteomes and cell function. Can wiki tools make a significant contribution to solving this problem? Can wikipedia provide an entry point for the world to the wealth of biological data that is currently hidden in obscure databases and journal articles?
 
|links=
As a first step for this project, we can create a standardized system for presenting information about [[protein]]s and [[gene]]s within wikipedia. A logical place to start is with a system for categorization of proteins, start here: [[Whole proteome analysis]]. (see also: [[EC number]], [[Talk:Protein#Separate page for protein nomenclatures?|protein nomenclature talk]], [[Talk:Protein#List of Proteins|talk about protein lists]], [[Talk:List of proteins]] and [[Talk:Ion channel|discussion about a specific class of non-enzyme proteins]]).
[[WP:WikiProject Molecular and Cell Biology/Resources|Resources]]
<br/>[[WP:WikiProject Molecular and Cell Biology/Statistics|Statistics]]
<br/>[[wikidata:Wikidata:WikiProject_Molecular_biology|Wikidata project]]
<br/>[[WP:WikiProject Molecular Biology/Molecular and Cell Biology/Historical|Historical pages]]
}}
 
<!--------------
For [[Biology#Classification of life|organismal biology]] evolutionary relatedness of organisms provides a way to categorize all organisms. For proteins, functional categories are probably best and that is what is emphasized at [[Whole proteome analysis]].
Body section
--------------->
{{col-begin}}
{{col-break}}
 
== How the project can help you ==
We can continue to develop the template for [[#Protein info box|protein information boxes]]. Protein information boxes can be included in each wikipedia article about a particular protein. Eventually, there should also be an information box about [[List of distinct cell types in the adult human body|cell types]].
 
<div style="float:left; width:100px; text-align:center; margin-left: 1.1em; margin-right: 1.1em;">
==Similar WikiProjects==
[[File:Speechbubbles icon.svg|50px|link=WT:MCB|alt=Discuss]]<br/>
The [[Wikipedia:List of WikiProjects|list of active projects]] has sections for both [[Wikipedia:List of WikiProjects#Biology|Biology]] and [[Wikipedia:List of WikiProjects#Health sciences|Health sciences]], but the most relevant seems to be the [[Wikipedia:WikiProject Clinical medicine|Medicine Project]] listed at the [[Wikipedia:Wikiportal/Biology|Biology Portal]] and the [[Wikipedia:Wikiportal/Medicine|Medicine Portal]]. Listed within the '''Medicine Project''', there is a [[Wikipedia:WikiProject Preclinical Medicine|Preclinical Medicine Project]] that is concerned with the kinds of basic science courses that medical students take, however, there is only minimal emphasis on the type of molecular and cell biology issues that are centered on fundamental concerns such as naming and categorizing genes, proteins and cell types.
</div><br />
Our&nbsp;[[WT:MCB|discussion&nbsp;page]]&nbsp;is&nbsp;a great hub for asking advice, bringing up ideas, suggesting articles for creation, and requesting reviews <br/>
{{clear}}<br />
 
<div style="float:left; width:100px; text-align:center; margin-left: 1.1em; margin-right: 1.1em;">
==Participants==
[[File:OOjs UI icon newspaper-ltr.svg|50px|link=WP:WikiProject_Molecular_and_Cell_Biology/Resources|alt=Advice & Resources]]<br/>
* [[User:JWSchmidt]]
</div><br />
* [[User:Jfdwolff]]
We&nbsp;keep&nbsp;a&nbsp;collection&nbsp;of [[/Resources|advice & resources]] pages on the challenges of writing science and molecular biology Wikipedia articles <br/>
* [[User:Adenosine]]
{{clear}}<br />
* [[User:Biohacker]]
* [[User:Stewartadcock]]
* [[User:JOK]]
* [[User:Nitramrekcap|Nitramrekcap]]
 
<div style="float:left; width:100px; text-align:center; margin-left: 1.1em; margin-right: 1.1em;">
==Structure==
[[File:OOjs UI icon unStar.svg|50px|link=WP:WikiProject Molecular and Cell Biology/Statistics|alt=Assessment & Statistics]]<br>
# Wikipedia articles about individual proteins or small protein families can be organized so as to look like [[Myoglobin]] or [[Rubisco]].
</div><br />
# Wikipedia articles about individual proteins or small protein families can each have a '''protein information box''' (see [[Myoglobin]] for an example).
[[/Statistics|Automatically&nbsp;updated&nbsp;lists]] of articles and significant updates can help you keep on top of important events and find stubs to expand <br/>
# Each Wikipedia articles about individual proteins or small protein families can be organized into one or more wikipedia category. See [[Whole proteome analysis]] for needed [[:Category:Proteins|protein categories]]. See [[Cytoskeleton]] and [[:Category:Cytoskeleton]] for an example.
{{clear left}}
# The main articles in each wikipedia protein category can be put into a '''navigation box''' (see the bottom of [[Cytoskeleton]] for an example).
{{col-break}}
<!--
== How you can help the project ==
Discuss the format for each article based on the WikiProject. Include various categories applicable to the topic.
-->
 
'''Improve our articles'''<br>
==Hierarchy definition==
:'''[[/Style guidelines#Infoboxes|Add Infoboxes]]''' – Help to standardise the data presented on [[:Category:Proteins|protein articles]] <br>
No classification of this project has been defined.
:'''[[/Diagram guide |Add images ]]''' – Diagrams and figures are particularly important to science articles so you can look at our [[WP:WikiProject Molecular and Cell Biology/Diagram guide|diagram guide]] for standardising protein and cell figures, or ask for help in creating and updating pictures on the [[WT:MCB|Talk page]] <br>
:'''[[WP:Attribution |Add references]]''' – Reliable citations are needed articles to be a [[WP:Attribution|verifiable]] source of information <br>
 
'''[[WT:MCB|Collaboration]]''' – Contribute to a team effort by participating in the collaborations that come up on our talk page to improve relevant articles to [[WP:FA|featured article]] status <br>
==Goals==
'''[[Template:Wikiproject MCB|Label articles of interest]]''' – Add pages to the project by putting the following template on the talk pages of all articles of interest to molecular and cell biology:
# Create a standard system for providing fundamental information about the proteins and cells that are mentioned and discussed in wikipedia articles.
:{{nowrap|{{tlx|WikiProject&nbsp;Molecular&nbsp;Biology|class{{=}}|importance{{=}}|<nowiki>MCB=yes</nowiki>|<nowiki>MCB-imp=<!--MCB importance--></nowiki>}}}} <br>
'''Adopt a stub''' – There are many, many stubby MCB articles that have potential, see [[:Category:Molecular and cellular biology stubs]] or [[:Category:Stub-Class MCB articles]].<br>
'''Categorisation''' – Add protein articles to the [[list of types of proteins]] and place them in the [[:Category:Proteins|proteins category]] or one of its subcategories. <br>
'''Recruitment''' – Assist in '''public relations and outreach''' by recruiting editors interested in molecular and cell to contribute to Wikipedia. <br>
'''Clean up articles''' – There is a list of articles requiring clean up at {{WikiProject cleanup list|Molecular and Cell Biology}}<br />
'''Create new articles'''
:New gene stubs for [[WP:notable]] genes can be created using a tool:
:#Look up the "Gene ID" number on [https://www.ncbi.nlm.nih.gov/gene NCBI Gene] for a missing gene entry in ''Homo sapiens''
:#Append that number to <code><nowiki>http://genewiki.sulab.org/wiki/article/create/</nowiki></code> (e.g., [[TAAR9]]: [https://www.ncbi.nlm.nih.gov/gene/?term=134860 134860] – http://genewiki.sulab.org/wiki/article/create/134860/)
:#Navigate to that url, click "Toggle Stub Code", and copy/paste the output into a new Wikipedia article about the gene
 
{{col-end}}
==Projects==
# Public relations/outreach. Ways need to be found to recruit more of the molecular and cell biologists of the world (and their students) to contribute to wikipedia.
# '''Categorization of articles about proteins'''. See [[Whole proteome analysis]].
# '''Organizing and upgrading articles about proteins'''. See [[#Infoboxes|the section on infoboxes]], below.
# '''Requested articles'''. List new wikipedia pages that are needed:
===Requested Articles===
*New wikipedia pages for [[granulysin]] and [[protocadherin]] are needed at [[Common chimpanzee]].
*New wikipedia pages for [[RuBisCO activase]] and [[CA1P-phosphatase]] are needed at [[RuBisCO]].
*New wikipedia pages for [[plakoglobin]], [[desmoplakin]], [[desmoglein]]s and [[desmocollin]]s are needed at [[Intermediate filament]].
*New wikipedia pages for [[ParM]] and [[Crescentin]] are needed at [[Cytoskeleton]].
*New wikipedia pages for [[Prestin]] and bacterial [[MotA]], [[MotB]], [[FliG]], [[FliM]], and [[FliN]] motor components are needed at [[Motor protein]].
*New wikipedia pages for more protein domains at [[Structural ___domain]].
*Wikipedia page is needed for basic term [[carrier protein]], [[carrier-protein]] or [[carrier (protein)]].
 
<!--------------
====More ways to "get the red out"====
Article alerts
*[[List of molecular biology topics]] <-- start articles for topics in red.
--------------->
 
== Article alerts ==
<!--This section is for organizing group projects-->
{{article alerts columns|Wikipedia:WikiProject Molecular Biology/Molecular and Cell Biology/Article alerts}}
 
==Tasks Participants ==
{{User WPMCB|float=right}}
[[Image:Pit1DNAbinding.png|thumb|right|Example of a GFDL image that can be used to illustrate protein structure.]]
There are two lists of project members
# Put links to this project in all of the correct places within wikipedia. This includes existing short articles about specific proteins and new stubs (see [[#Stub templates]]) for other proteins that are currently only mentioned in other wikipedia articles. '''Note on finding existing articles about proteins and mentioned proteins''': search wikipedia for "protein"; many proteins are mentioned in this sort of context: "the protein X", "a protein called Y" etc. On 8/30/05 I ([[User:JWSchmidt]]) went through the first 50 Google hits for "protein" in wikipedia, placing some [[#Stub templates|stub templates]] (see below) and adding to [[List of proteins]]. '''See also''': [[Wikipedia:Requested articles/Natural Sciences#Proteins|requested protein articles]]. '''Note''': many enzymes can be found in the wikipedia [[:Category:Enzymes|enzymes category]].
:You may <span class="plainlinks">[https://en.wikipedia.org/w/index.php?title=WP:WikiProject_Molecular_Biology/Molecular_and_Cell_Biology/Participants&veaction=edit add yourself]</span> and your interests to this manually-updated [[WP:WikiProject_Molecular_Biology/Molecular_and_Cell_Biology/Participants|members list]] in alphabetical order.
# expand stubs [[:Category: Molecular and cellular biology stubs|Molecular and cellular biology stubs]]<BR>It seems a reasonable goal to have each wikipedia article that is about a particular protein include a paragraph that expands on each item in the corresponding protein information box. In other words, the protein information box can serve as a standard-format summary of many of the key topics in the full article.
:There is also an automatically-updated list of [[WP:WikiProject_Directory/Description/WikiProject_Molecular_and_Cell_Biology#Active_WikiProject_Participants|currently active participants]].<br>
# As protein information boxes are added to pages about specific proteins, be sure to add them to the [[List of proteins]].
You're also welcome to add the userbox <code>{{tl|User MCB}}</code> to your userpage.
# There are also pages dealing with protein structural domains such as [[Homeobox]]. Maybe there should be an optional infobox template just for protein structural domains.
# '''Images'''. The [[Homeobox]] article is a good example of a page that contains an image that is for non-commercial use. The [[Oxytocin]] article contains a similar image that may also be a problem. I suggest that all such images that were derived from images that were archived at the PDB website (and were covered by their non-commercial uses disclaimer) be replaced by molecular model images generated by wikipedia users themselves from the raw structural data in the Protein Data Base. The image to the right is an example of such an image. The [[Protein Data Bank]] says, "The contents of PDB are in the public ___domain. Online and printed resources are welcome to include PDB data and images from the Structure Explorer pages, as long as they are not for sale as commercial items themselves, and their corresponding citations are included." ([http://www.rcsb.org/pdb/citing.html source]) Also see: [[:Category:Protein images]].
#Protein-containing macromolecular complexes like [[ribosome]] should also be organized.
#Make sure that all articles about proteins are placed in the [[:Category:Proteins|Proteins category]] or lower level categories that are subcategories of the '''Proteins category'''. Additional categories: [[Whole proteome analysis]].
 
{| cellspacing="0" width="100%" style="border-collapse: collapse; border: 1px solid #770000;"
<!--For anything smaller or more specific than projects and anything that individuals can work on. Usually this is a list of individual articles. See [[Wikipedia:WikiProject Melbourne#Open tasks]] for one example of how this section can be used.-->
! style="border: 1px solid #770000; font-size: 110%; color: #FFF; background-color: #770000;" width=11% | &nbsp;&nbsp;Name
 
! style="border: 1px solid #770000; font-size: 110%; color: #FFF; background-color: #770000;" width=6% | &nbsp;&nbsp;Talk page
==Adopt an article==
! style="border: 1px solid #770000; font-size: 110%; color: #FFF; background-color: #770000;" | &nbsp;&nbsp;Special interests
Similar to the [[Wikipedia:Collaboration of the week|Collaboration of the week]], but on a smaller scale, you might want to "adopt" an article. This would involve doing the research, writing, and picture-taking (if possible) for either a non-existent article or a stub. Of course, everyone else can still edit an adopted article, and you can work on other things too, but the idea is to find a focus for a while, to try and build up the number of quality articles the Project has produced.
* [[Example|Example article]]: [[User:Example]]
*
<!--Check [[Wikipedia:WikiProject Melbourne#Adopt an article]] to see how this section is used.-->
 
==General strategy and discussion forums==
*[[/General]]
*[[/Strategy]]
 
==Other subpages==
 
==Templates==
 
===Infoboxes===
{{Protbox start|Name=[[Myoglobin]]|Photo=Myoglobin.png|Caption=Model of helical domains in myoglobin.|Gene=[[HUGO]] code: [http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=HGNC:6915 MB]|Structure= [http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?form=6&db=t&Dopt=s&uid=3278 molecular structure]|Review=[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15548893&query_hl=13 role in human pathologies], [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14656764&query_hl=26 gene knockout]}}
{{Protbox function|Type=[[Hemoprotein]]|Functions= [[oxygen]] storage/transport|Domains= [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?ascbin=2&maxaln=10&seltype=3&uid=27699&aln=4,0,2,48,48,52,31,82,83,14,96,98,44&querygi=231160&querynm=5mbn+(query) globin]|Diseases= [[kidney]] disease, [[vasospasm]]}}
{{Protbox ___location|Taxa=many [[metazoan]] [[phylum (biology)|phyla]], ''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1459874 Archaea]''?, [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=886402 protozoan/eubacterial]?|Cells=[[muscle]] cells|Location=[[cytoplasm]]}}
{{Protbox other|Mods= [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15104207&query_hl=36 glycation]?, [[phosphorylation]] in [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15050527&query_hl=34 whales]?|Names= '''myoglobin-like proteins''' in [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14560666&query_hl=44 microorganisms]|Interactions= [[oxygen]], [[carbon monoxide]], [[nitric oxide]]|Pages= [[X-ray crystallography]], [[Secondary structure]]}}
{{Protbox finish}}
 
====Protein info box====
Info box example for the protein myoblobin (to right).<BR>
Note: only the first (start) and last (finish) template are required. The middle three templates (function, ___location, other) are options.
 
<nowiki>{{</nowiki>[[Template:Protbox start|Protbox start]]<nowiki>}}</nowiki> template:
*preferred name of the protein
*image for protein (might be structural diagram, cell localization, etc)
*caption for image
*link to gene(s) in database, which gene(s) code for it?
*link to database entry for protein structural info
*links to recent articles at [[Entrez]] PubMed.
 
<nowiki>{{</nowiki>[[Template:Protbox function|Protbox function]]<nowiki>}}</nowiki> template:
*categorization of the protein; what type of protein is it?
*functions of the protein
*structural domains in the protein
*disease conditions involving the protein
 
<nowiki>{{</nowiki>[[Template:Protbox ___location|Protbox ___location]]<nowiki>}}</nowiki> template:
*taxonomic range of expression (wide? restricted?)
*which types of cells express it?
*Subcellular localization.
 
<nowiki>{{</nowiki>[[Template:Protbox other|Protbox other]]<nowiki>}}</nowiki> template:
*covalent modifications with functional significance
*all names that have been applied to the protein
*what other molecules interact with it?
*links to wikipedia pages that discuss the protein
 
<nowiki>{{</nowiki>[[Template:Protbox receptor|Protbox receptor]]<nowiki>}}</nowiki> template:
*Receptor actions, e.g. vasoconstriction, neuronal excitation, etc.
*Agonists
*Antagonists
 
<nowiki>{{</nowiki>[[Template:Protbox finish|Protbox finish]]<nowiki>}}</nowiki> template:
*This template simply marks the end of a protein information box. (required)
 
====Cell type info box====
This will be an information box for displaying basic information about individual cell types.
 
Some useful references:
*[http://obo.sourceforge.net/cgi-bin/detail.cgi?cell open source cell type ontology project]
*http://www.bioeng.auckland.ac.nz/anatml/anatml/database/cells/cells/index.html
*[http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_c_18zPzhtm Cell types from Dorland's Medical Dictionary]
 
Basic info could be, name(s), functions, what taxonomic groups has the cell type, etc.<BR>
Tissue type(s) that contain the cell type<BR>
The major types of proteins that are expressed and that provide the specialized functions of the cell type
 
I suggest we pick one cell type as an example and get started. I propose [[Muscle fiber|skeletal muscle]].
 
====Small molecules====
We definately need infoboxes that can satisfy both us, the molecular biologists, and the chemists. There are currently two code distinct infoboxes on the "market" - format styles I and II.
 
:2. Format style I, used in several variations, has the following code (on the left) and result (on the left):
 
<table style="width: 100%"><tr><td style="vertical-align: top;">
<nowiki>
{| align="right" cellspacing="0" cellpadding="3" style="background: #FFFFFF; border: 1px solid #C0C090; border-collapse: collapse; margin: 0 0 0.5em 0.5em; width: 320px;"
! {{chembox header}}| '''{{PAGENAME}}''' <!-- replace if not identical with the article name --></nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| align="center" colspan="2" bgcolor="#ffffff" | [[Image:{{PAGENAME}}.gif|{{PAGENAME}}]] <!-- replace if not identical with the pagename --></nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| style="vertical-align: top;" | [[IUPAC nomenclature|Chemical name]]</nowiki><br /><nowiki>
| style="width: 100%;" | 2-(carbamimidoyl-methyl-amino)acetic acid </nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| style="vertical-align: top;" | Synonyms</nowiki><br /><nowiki>
| (&alpha;-methylguanido)acetic acid<br/>Creatin<br/>Kreatin<br/>methylguanidinoacetic acid<br/>N-amidinosarcosine</nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| style="vertical-align: top; white-space: nowrap;" | [[Chemical formula]]</nowiki><br /><nowiki>
| C<sub>4</sub>H<sub>9</sub>N<sub>3</sub>O<sub>2</sub></nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| [[Simplified molecular input line entry specification|SMILES]] </nowiki><br /><nowiki>
| CN(CC(=O)O)C(=N)N</nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| [[Molecular mass]]</nowiki><br /><nowiki>
| 131.133 g/mol</nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| style="vertical-align: bottom;" | [[Density]]</nowiki><br /><nowiki>
| ? g/cm<sup>3</sup></nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| [[Melting point]]</nowiki><br /><nowiki>
| ? °C</nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| [[Boiling point]]</nowiki><br /><nowiki>
| ? °C</nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| style="vertical-align: top;" | [[Acid dissociation constant|p''K''<sub>a</sub>]]</nowiki><br /><nowiki>
| style="vertical-align: top;" | ?</nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| [[CAS registry number|CAS number]]</nowiki><br /><nowiki>
| 57-00-1</nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
| [[EINECS number]]</nowiki><br /><nowiki>
| 200-306-6</nowiki><br /><nowiki>
|-</nowiki><br /><nowiki>
|}
</nowiki>
</td><td style="vertical-align: top;">
{| align="right" cellspacing="0" cellpadding="3" style="background: #FFFFFF; border: 1px solid #C0C090; border-collapse: collapse; margin: 0 0 0.5em 0.5em; width: 320px;"
! {{chembox header}}| '''{{PAGENAME}}''' <!-- replace if not identical with the article name -->
|-
| align="center" colspan="2" bgcolor="#ffffff" | [[Image:{{PAGENAME}}.gif|{{PAGENAME}}]] <!-- replace if not identical with the pagename -->
|-
| style="vertical-align: top;" | [[IUPAC nomenclature|Chemical name]]
| style="width: 100%;" | 2-(carbamimidoyl-methyl-amino)acetic acid
|-
| style="vertical-align: top;" | Synonyms
| (&alpha;-methylguanido)acetic acid<br/>Creatin<br/>Kreatin<br/>methylguanidinoacetic acid<br/>N-amidinosarcosine
|-
| style="vertical-align: top; white-space: nowrap;" | [[Chemical formula]]
| C<sub>4</sub>H<sub>9</sub>N<sub>3</sub>O<sub>2</sub>
|-
| [[Simplified molecular input line entry specification|SMILES]]
| CN(CC(=O)O)C(=N)N
|-
| [[Molecular mass]]
| 131.133 g/mol
|-
| style="vertical-align: bottom;" | [[Density]]
| ? g/cm<sup>3</sup>
|-
| [[Melting point]]
| ? °C
|-
| [[Boiling point]]
| ? °C
|-
| style="vertical-align: top;" | [[Acid dissociation constant|p''K''<sub>a</sub>]]
| style="vertical-align: top;" | ?
|-
| [[CAS registry number|CAS number]]
| 57-00-1
|-
| [[EINECS number]]
| 200-306-6
|-
|colspan=4|
<div style="height: 300px; overflow: auto; border:0px; padding: 3px; text-align: left; background-color:#EEEEEE">
{{/Participants}}</div>
|}
</td></tr>
</table>
 
:2. II, which i am "advocating", and which uses ideas from other info boxes, has the following:
 
<table style="width: 100%"><tr><td style="vertical-align: top;">
<nowiki>
{{NatOrganicBox_header | image=Creatine.gif | width=320px | name=Creatine }}</nowiki><br /><nowiki>
{{OrganicBox_name | 2-(carbamimidoyl-methyl-amino)acetic acid }}</nowiki><br /><nowiki>
{{OrganicBox_synonyms | Creatin<br />Kreatin<br />Krebiozon<br />Methylglycocyamine<br />N-amidinosarcosine<br />N-methyl-N-guanylglycine<br />Pyrolysate }}</nowiki><br /><nowiki>
{{OrganicBox_abbreviations | Cr }}</nowiki><br /><nowiki>
{{OrganicBox_formula | C<sub>4</sub>H<sub>9</sub>N<sub>3</sub>O<sub>2</sub> }}</nowiki><br /><nowiki>
{{NatOrganicBox_section_physicalprop}}</nowiki><br /><nowiki>
{{OrganicBox_mass | 131.133 }}</nowiki><br /><nowiki>
{{OrganicBox_density | ? }}</nowiki><br /><nowiki>
{{OrganicBox_melt_point | ? }}</nowiki><br /><nowiki>
{{OrganicBox_boil_point | ? }}</nowiki><br /><nowiki>
{{NatOrganicBox_section_chemprop}}</nowiki><br /><nowiki>
{{OrganicBox_isoelectric_point | ? }}</nowiki><br /><nowiki>
{{OrganicBox_pka | ? }}</nowiki><br /><nowiki>
{{OrganicBox hbond acceptor | 5 }}</nowiki><br /><nowiki>
{{OrganicBox_hbond_donor | 3 }}</nowiki><br /><nowiki>
{{OrganicBox_tautomers | ? }}</nowiki><br /><nowiki>
{{NatOrganicBox_section_miscellaneous}}</nowiki><br /><nowiki>
{{OrganicBox_CAS | 57-00-1 }}</nowiki><br /><nowiki>
{{OrganicBox_EINECS | 200-306-6 }}</nowiki><br /><nowiki>
{{OrganicBox_PubCnem | 586 }}</nowiki><br /><nowiki>
{{NatOrganicBox_footer}}
</nowiki>
</td><td style="vertical-align: top;">
{{NatOrganicBox_header | image=Creatine.gif | width=320px | name=Creatine }}
{{OrganicBox_name | 2-(carbamimidoyl-methyl-amino)acetic acid }}
{{OrganicBox_synonyms | Creatin<br />Kreatin<br />Krebiozon<br />Methylglycocyamine<br />N-amidinosarcosine<br />N-methyl-N-guanylglycine<br />Pyrolysate }}
{{OrganicBox_abbreviations | Cr }}
{{OrganicBox_formula | C<sub>4</sub>H<sub>9</sub>N<sub>3</sub>O<sub>2</sub> }}
{{NatOrganicBox_section_physicalprop}}
{{OrganicBox_mass | 131.133 }}
{{OrganicBox_density | ? }}
{{OrganicBox_melt_point | ? }}
{{OrganicBox_boil_point | ? }}
{{NatOrganicBox_section_chemprop}}
{{OrganicBox_isoelectric_point | ? }}
{{OrganicBox_pka | ? }}
{{OrganicBox hbond acceptor | 5 }}
{{OrganicBox_hbond_donor | 3 }}
{{OrganicBox_tautomers | ? }}
{{NatOrganicBox_section_miscellaneous}}
{{OrganicBox_CAS | 57-00-1 }}
{{OrganicBox_EINECS | 200-306-6 }}
{{OrganicBox_PubCnem | 586 }}
{{NatOrganicBox_footer}}
</td></tr>
</table>
 
 
I initially used format style I, but as i was tryig to make the tables look standart and all i realized that i couldn't do it this way, b/c if i needed to add a new change to the way the table looked in all of the articles that had it so far (say add a link, or border, or anything) i had to go and edit each one of them. When the number of these articles is low that's not a problem but if this standart table is to be used for all the compounds produced by the cell - tens of hundreds if not thousands, then that's a major headache. So i learned about the templates and created format style II, which design by the way looks similar to the one used for the chemical element's "info table". Now if i need to make any change all i need to do is to change the appropriate template and that will affect all the articles that use it. Certainly, Style II is not in its final edition, more changes will be added to it to suit both the biologists and the chemists, as i would realy, hmmm dislike, if the info table contains chemical data only and lacks any biological one - the info for the melting and boiling points, or for any of the solid properties (i'm going to add these later) don't really "heat the soup" for the biologists, we also need stuff like - [[Hydrogen bond|H-bond]] donor count.
About "EINECS", i added it b/c it was already in the info, i didn't know what it ment. If it is not used anymore then i'll stop using it too.
I didn't write the code that adds the article's name on the top of the table b/c having a table named "Creatine" in an article called "Creatine" is redundant. But if you insist i will add it and here is the exmple of the power of the templates - i will change the template [[Template:NatOrganicBox_header|<nowiki>{{NatOrganicBox_header}}</nowiki>]] and all the articles that use it will be affected. [[User:BorisTM|BorisTM]] 19:28, 2 November 2005 (UTC)
 
====Database templates====
Templates like this (<nowiki>{{</nowiki>[[Template:OMIM|OMIM]]<nowiki>}}</nowiki>) for the [[Protein Data Bank|Protein database]]s, Enzyme Number and [[Entrez|PubMed]].
 
----
 
'''Human genetics for a protein/gene:'''<BR>
Example: <nowiki>{{OMIM|160000}}</nowiki><BR>
{{OMIM|160000}}
 
----
 
'''[[Digital object identifier]]'''<BR>
Example: <nowiki>{{Doi|10.1038/437794a}}</nowiki><BR>
{{Doi|10.1038/437794a}}
 
----
 
 
'''[[EC number|Enzyme number]]''':<BR>
Example: <nowiki>{{EC number|4.1.1.39}}</nowiki><BR>
{{EC number|4.1.1.39}}
 
----
 
'''Template for [[Protein Data Bank]] citations. Example''':
 
Example: <nowiki>{{Protein Data Bank|9RUB}}</nowiki>
 
{{Protein Data Bank|9RUB}}
 
----
 
'''Template for [[PubMed Central]] full text articles'''<BR>
Example: <nowiki>{{PMC|137841}}</nowiki>
 
{{PMC|137841}}
 
----
 
'''Template for [[Entrez]] PubMed citations'''<BR>
Example:<nowiki>{{Entrez Pubmed|10336462}}</nowiki>
 
{{Entrez Pubmed|10336462}}
 
:There is no need for that. Typing PMID with the code will render automatically as with ISBNs, like this - PMID 1234567890 [[User:Jfdwolff|JFW]]&nbsp;|&nbsp;[[User_talk:Jfdwolff|<small>T@lk</small>]] 21:27, 31 August 2005 (UTC)
::The [[Template:Entrez Pubmed|Entrez Pubmed]] template is better because it does not subject the reader to an unexplained abbreviation (PMID) and it provides a link to a wikipedia page that talks about the database being linked to. --[[User:JWSchmidt|JWSchmidt]] 22:47, 31 August 2005 (UTC)
 
====Protein topics navigation boxes====
See [[User:Lilious]] for how to jazz up such navigation boxes.
 
Templates:
 
<nowiki>{{</nowiki>[[Template:Protein topics|Protein topics]]<nowiki>}}</nowiki>
{{Template:Protein topics}}
 
<nowiki>{{</nowiki>[[Template:Protein methods|Protein methods]]<nowiki>}}</nowiki> [[Protein methods]]
{{Template:Protein methods}}
 
<nowiki>{{</nowiki>[[Template:Protein domains|Protein domains]]<nowiki>}}</nowiki>
{{Template:Protein domains}}
 
<nowiki>{{</nowiki>[[Template:Cytoskeletal Proteins|Cytoskeletal Proteins]]<nowiki>}}</nowiki>
{{Template:Cytoskeletal Proteins}}
 
====Research topic navigation boxes====
Example: <nowiki>{{King's College DNA}}</nowiki><BR>
{{King's College DNA}}
====What is a subtemplate?====
* {{substemplate|template}}
* e.g.<nowiki>{{</nowiki>Infobox Molecular and Cellular Biology<nowiki>}}</nowiki>
{{template|Infobox Molecular and Cellular Biology }}
 
<br style="clear: both">
 
===Stub templates===
====For new articles====
<nowiki>{{</nowiki>[[Template:Molcellbio-stub|Molcellbio-stub]]<nowiki>}}</nowiki><BR>
Puts the new stub article in '''Category: Molecular and cellular biology stubs'''
{{Molcellbio-stub}}
====Add to existing short articles====
<nowiki>{{</nowiki>[[Template:Molecular and Cellular Biology-stub|Molecular and Cellular Biology-stub]]<nowiki>}}</nowiki>
{{Molecular and Cellular Biology-stub}}
 
<!--stubs are managed by the [[WP:WSS:Stub-sorting WikiProject]]. *To propose new stub categories/templates, see [[Wikipedia:WikiProject Stub sorting/Criteria#Proposed new stubs|Stub sorting criteria: Proposed new stubs]].-->
 
===Other templates===
 
 
====Add to existing categories====
<nowiki>{{</nowiki>[[Template:Molecular and Cellular Biology-category|Molecular and Cellular Biology-category]]<nowiki>}}</nowiki>
{{Molecular and Cellular Biology-category}}
 
====Mark articles that are part of this project====
<nowiki>{{</nowiki>[[Template:templateMolecular and Cellular Biology|templateMolecular and Cellular Biology]]<nowiki>}}</nowiki>
{{templateMolecular and Cellular Biology }}
 
====circulatory system====
{{Blood}}
 
==Categories==
*[[:Category:Molecular and Cellular Biology|Molecular and Cellular Biology]]
*[[:Category:Molecular and cellular biology stubs|Molecular and cellular biology stubs]]
 
===protein families===
There needs to be a category for each [[protein family]] at the [[Whole proteome analysis]] article Also, a navigation bar template (see templates, above).
 
====[[Cytoskeleton]]====
This template: <nowiki>{{</nowiki>[[Template:Cytoskeletal Proteins]]<nowiki>}}</nowiki>
marks articles as being in the '''Cytoskeleton''' category.
*[[:Category:Cytoskeleton|Cytoskeleton category]]
====Other categories====
*[[:Category:Motor proteins]]
 
==Lists==
*[[List of proteins]]
*[[List of biomolecules]]
 
==Requests==
*see [[#protein families]]
*see [[#Requested Articles]]
 
==Resources==
 
==Molecular and Cellular Biology [[Wikipedia:Meetups|Meetups]]==
 
==Archives==
*[[/Archive1|#1]]
==Sister Project links==
<table border=0 rows=1 cols=2 width=100%>
<tr>
<td width=50% valign=top>
{{commons|Molecular and Cellular Biology }}
{{Commonscat|Molecular and Cellular Biology }}
{{Wikiquote}}<!--{{Wikiquotepar|Molecular and Cellular Biology }}-->
{{Wiktionary}}<!--{{Wiktionarypar|Molecular and Cellular Biology }}-->
{{Wikinews|Molecular and Cellular Biology }}
{{Wikinewscat|Molecular and Cellular Biology }}
 
</td>
<td width=50% valign=top>
{{wikibooks}}<!--{{Wikibookspar||Molecular and Cellular Biology }}-->
{{Wikisource}}<!--{{WikisourceparMolecular and Cellular Biology }}, {{Wikisource author|Molecular and Cellular Biology }}, {{Wikisource1911Enc|Molecular and Cellular Biology }}-->
{{Wikispecies|Molecular and Cellular Biology }}
{{Meta|Molecular and Cellular Biology }}
 
</td></tr>
</table>
 
 
<!--------------
{{Template:Sisterlinks|Molecular and Cellular Biology }}
Navboxes
--------------->
{{Help navigation}}
{{Wikipedia policies and guidelines|state=collapsed}}
{{WikiProject Footer}}
{{DEFAULTSORT:MOLECULAR AND CELLULAR BIOLOGY}}
[[Category:Molecular and Cell Biology task force| ]]
[[Category:WikiProject Molecular Biology]]
[[Category:WikiProjects participating in Wikipedia 1.0 assessments]]
 
<!----------------------------
[[Category:WikiProjects|Molecular and Cellular Biology]][[Category:Molecular and Cellular Biology]]
Igor processing directives
Please do not alter
------------------------------
<igor>
<project-templates update-to-preferred="true">
<project-template template="WikiProject Molecular and Cell Biology" />
<project-template template="Wikiproject MCB" />
<project-template template="WikiProject MCB" />
<project-template template="Wikiproject mcb" />
<project-template template="MCB" />
<project-template template="WPMCB" />
</project-templates>
</igor>
----------------------------->