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'''Latent semantic structure indexing''' ('''LaSSI''') is a technique for calculating chemical similarity derived from [[latent semantic analysis]] (LSA).
LaSSI was developed at [[Merck & Co.]] and patented in 2007<ref>
== Overview ==
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== References ==
{{Reflist}}
* Hull, R.D., Fluder, E.M., Singh, S.B., Nachbar, R.B., Sheridan, R.P. and Kearsley, S.K. (2001) "Latent semantic structure indexing (LaSSI) for defining chemical similarity." J Med Chem, 2001 Apr 12;44(8):1177–84. {{doi|10.1021/jm000393c}}
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