Talk:Lithium (medication): Difference between revisions

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I'm going to redirect the lithium salts page to here, since it was not really about lithium salts per se, but only their use as mood stabilizing drugs.

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==Effectiveness of Lithium therapy==

i still think this is the best mood stabilizer, even though i was in intensive care for 2weeks after accidental overdose... it's extremely easy to die off of this if not taken properly, especially if it's in a time-released tablet... i don't know how it's done at other hospitals, but i was put on kidney dialysis to clear all the lithium from my blood... -- [[User:Lieutenant Colonel Frank Slade|Lieutenant Colonel Frank Slade]] 02:01, 10 July 2006 (UTC)

Regarding the removal of "It is the only [[antidepressant]] effective in treating the [[manic episode]]s seen in [[bipolar disorder]]." Lithium is not an anti-depressant. Lithium is also not effective in quelling manic episodes in progress despite the claim in Goodwin and Jamison's outdated 1991 edition of Manic Depression.

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i'm not going to edit this page, but I'd have the first line say something like "The use of lithium salts to treat mania was first introduced by physicians of ancient Rome, when doctors recommended bathing in the springs in northern Italy which are abundant with the salts." ... I just have no citation but I've read it time and time again

Has anyone seen scientifically valid primary studies on the effectiveness of lithium for managing manic depression? I have not and it was ineffective during my decade long experience with lithium. See the "Patient Notes" at the end of the article.

== Psychotropic effects ==

A previous editor changed the word "psychoactive" in the following sentence to "recreational":

<blockquote>

:"Unlike other psychoactive drugs, Li+ produces no obvious psychotropic effects, (such as euphoria) in normal individuals at therapeutic concentrations."

Please see:

Lithium does not induce euphoria, hallucinations, or psychosis at therapeutic doses -- its undesired side-effects are almost completely negative in nature, something which is not true of most other psychoactive drugs. There's certainly no danger of lithium ever being misused as a recreational drug. -- [[User:The Anome|The Anome]] 09:33, 27 October 2006 (UTC)

* McIntyre RS, Mancini DA, Parikh S, Kennedy SH. "Lithium revisited." Can J Psychiatry. 2001 May;46(4):322-7.

* Bowden CL, Brugger AM, Swann AC, Calabrese JR, Janicak PG, Petty F, and others. Efficacy of divalproex vs lithium and placebo in the treatment of mania. JAMA 1994;271:918–24.

This is just a start on the literature: the first reference is a review of the state of the art as of 2001.

Note that not everyone responds to the same drugs; many lithium non-responders are moved to other drugs for this reason. -- [[User:The Anome|The Anome]] 21:12, 10 Dec 2003 (UTC)

</blockquote>

:: I understand that it is considered the mood stabiliser of choice by most specialists in bipolar disorder, because it is the best documented, and it is believed to be effective for the highest proportion of patients. Nonetheless, the fact that the effective dosage of lithium is so close to the level at which it becomes dangerously toxic is a serious concern with the medication -- not a purely intellectual concern for me since my father died of a lithium overdose -- and the article should bring attention to this. ---- [[User:Chalst|Charles Stewart]] 12:50, 19 Aug 2004 (UTC)

::: <i>Lithium salts, with the exception of lithium orotate, have a narrow therapeutic/toxic ratio</i> -- OK, I missed this first read. This section might do with some changes to avoid unnecessarily technical terms ---- [[User:Chalst|Charles Stewart]] 12:56, 19 Aug 2004 (UTC)

== "Lithium salt" listed at [[Wikipedia:Redirects for discussion|Redirects for discussion]] ==

[[File:Information.svg|30px]]

An editor has identified a potential problem with the redirect [[:Lithium salt]] and has thus listed it [[Wikipedia:Redirects for discussion|for discussion]]. This discussion will occur at [[Wikipedia:Redirects for discussion/Log/2022 October 27#Lithium salt]] until a consensus is reached, and readers of this page are welcome to contribute to the discussion. <!-- from Template:RFDNote --> <span class="nowrap"> <span style="font-family:courier">-- [[User:Tamzin|<span style="color:#E6007A">Tamzin</span>]]</span>^{[''[[User talk:Tamzin|<span style="color:#E6007A">cetacean needed</span>]]'']} (she&#124;they&#124;xe)</span> 23:45, 27 October 2022 (UTC)

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