'''Hypodermin C''' ({{EC number|3.4.21.49}}, ''Hypoderma collagenase'') is an [[enzyme]].<ref>{{cite journal | vauthors = Lecroisey A, Boulard C, Keil B | title = Chemical and enzymatic characterization of the collagenase from the insect ''Hypoderma lineatum'' |author1= Lecroisey, A. |author2 =Boulard, C. |author3journal =Keil,B.European |journalJournal =of Eur. J. Biochem.Biochemistry |year= 1979 |volume = 101 | issue = 2 | pages = 385–393385–93 | date = November 1979 | pmid = 230030 | doi = 10.1111/j.1432-1033.1979.tb19730.x | doi-access = free }}</ref><ref>{{cite journal | vauthors = Lecroisey A, Keil B | title = Specificity of the collagenase from the insect ''Hypoderma lineatum'' |author1= Lecroisey, A. |author2 =Keil, B. |journal = Eur.European J.Journal Biochem.of |yearBiochemistry =| 1985 |volume = 152 | issue = 1 | pages = 123–130123–30 | date = October 1985 | pmid = 2995028 | doi = 10.1111/j.1432-1033.1985.tb09171.x | doi-access = free }}</ref><ref>{{cite journal | vauthors = Lecroisey A, Gilles AM, De Wolf A, Keil B | title = Complete amino acid sequence of the collagenase from the insect ''Hypoderma lineatum'' |author1 journal = Lecroisey,The A.Journal |author2of =Gilles,Biological A.-M.Chemistry |author3 volume =DeWolf, A.262 |author4 issue =Keil,B.16 |journal pages = J. Biol. Chem.7546–51 |year date = June 1987 |volume= 262 |issuedoi = 1610.1016/S0021-9258(18)47600-4 |pages doi-access = 7546–7551free | pmid = 3034899 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]
: [[Hydrolysis]] of proteins including native [[collagen]] at -Ala bond leaving an [[N-terminal]] (75%) and a [[C-terminal]] (25%) fragment
This enzyme is isolated from the [[larva]] of a [[warble fly]], ''[[Hypoderma lineatum]]''.
== References ==
Line 23 ⟶ 22:
{{Serine endopeptidases}}
{{Enzymes}}
{{Portal bar|Molecular and Cellular Biology|border=no}}