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Due to the importance of setting in early [[psychedelic therapy]], Hubbard introduced a "treatment space decorated to feel more like a home than a hospital", which came to be known as a "Hubbard Room".<ref>{{cite book |title=How to Change Your Mind |first=Michael |last=Pollan |date=15 May 2018 |authorlink=Michael Pollan |isbn=9780525558941 |page=164 |url=https://books.google.com/books?id=3vk5DwAAQBAJ&pg=PA164 |quote=But though this mode of therapy would become closely identified with Osmond and Hoffer, they themselves credited someone else for critical elements of its design, a man of considerable mystery with no formal training as a scientist or therapist: Al Hubbard. A treatment space decorated to feel more like a home than a hospital came to be known as a Hubbard Room, and at least one early psychedelic researcher told me that this whole therapeutic regime, which is now the norm, should by all rights be known as "the Hubbard method." Yet Al Hubbard, a.k.a. "Captain Trips" and "the Johnny Appleseed of LSD," is not the kind of intellectual forebear anyone doing serious psychedelic science today is eager to acknowledge, much less celebrate.}}</ref>
In 1966, Timothy Leary conducted a series of experiments with [[dimethyltryptamine]] (DMT) with controlled set and setting. The aim was to see whether DMT, which had then been mostly thought of as a terror-inducing drug, could produce pleasant experiences under a supportive set and setting. It was found that it could.{{ref|Leary1966}}
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