Non-coding RNA: Difference between revisions

Revision as of 15:49, 26 October 2022

Revision as of 15:51, 26 October 2022

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[[File:Yeast tri-snRNP.jpg|thumb|left|Electron microscopy images of the yeast spliceosome. Note the bulk of the complex is in fact ncRNA.]]

In eukaryotes, the [[spliceosome]] performs the [[RNA splicing|splicing]] reactions essential for removing [[intron]] sequences, this process is required for the formation of mature [[mRNA]]. The [[spliceosome]] is another RNP often also known as the [[snRNP]] or tri-snRNP. There are two different forms of the spliceosome, the major and minor forms. The ncRNA components of the major spliceosome are [[U1 snRNA|U1]], [[U2 snRNA|U2]], [[U4 snRNA|U4]], [[U5 snRNA|U5]], and [[U6 snRNA|U6]]. The ncRNA components of the minor spliceosome are [[U11 snRNA|U11]], [[U12 snRNA|U12]], [[U5 snRNA|U5]], [[U4atac minor spliceosomal RNA|U4atac]] and [[U6atac minor spliceosomal RNA|U6atac]].{{citation needed|date=June 2017}}

Another group of introns can catalyse their own removal from host transcripts; these are called self-splicing RNAs. There are two main groups of self-splicing RNAs: [[group I catalytic intron]] and [[group II catalytic intron]]. These ncRNAs catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms.{{citation needed|date=June 2017}}