Non-coding RNA: Difference between revisions

Revision as of 18:21, 31 August 2023

Revision as of 21:20, 7 November 2023

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==Biological roles==

Noncoding RNAs belong to several groups and are involved in many cellular processes.<ref name="Monga">{{cite journal | vauthors = Monga I, Banerjee I| title = Computational Identification of piRNAs Using Features Based on RNA Sequence, Structure, Thermodynamic and Physicochemical Properties | journal = Current Genomics | volume = 20 | issue = 7 | pages = 508–518 | date = November 2019 | pmid = 32655289| doi = 10.2174/1389202920666191129112705 | pmc = 7327968 }}</ref> These range from ncRNAs of central importance that are conserved across all or most cellular life through to more transient ncRNAs specific to one or a few closely related species. The more conserved ncRNAs are thought to be [[molecular fossilsfossil]]s or relics from the [[LUCA|last universal common ancestor]] and the [[RNA world hypothesis|RNA world]], and their current roles remain mostly in regulation of information flow from DNA to protein.<ref name="pmid9419222">{{cite journal | vauthors = Jeffares DC, Poole AM, Penny D | title = Relics from the RNA world | journal = Journal of Molecular Evolution | volume = 46 | issue = 1 | pages = 18–36 | date = January 1998 | pmid = 9419222 | doi = 10.1007/PL00006280 | bibcode = 1998JMolE..46...18J | s2cid = 2029318 }}</ref><ref name="pmid9419221">{{cite journal | vauthors = Poole AM, Jeffares DC, Penny D | title = The path from the RNA world | journal = Journal of Molecular Evolution | volume = 46 | issue = 1 | pages = 1–17 | date = January 1998 | pmid = 9419221 | doi = 10.1007/PL00006275 | bibcode = 1998JMolE..46....1P | s2cid = 17968659 }}</ref><ref name="pmid10497339">{{cite journal | vauthors = Poole A, Jeffares D, Penny D | title = Early evolution: prokaryotes, the new kids on the block | journal = BioEssays | volume = 21 | issue = 10 | pages = 880–9 | date = October 1999 | pmid = 10497339 | doi = 10.1002/(SICI)1521-1878(199910)21:10<880::AID-BIES11>3.0.CO;2-P | s2cid = 45607498 }}</ref>

===In translation===