This algorithm interacts badly with [[TCP delayed acknowledgment]]s (delayed ACK), a feature introduced into TCP at roughly the same time in the early 1980s, but by a different group. With both algorithms enabled, applications that do two successive writes to a TCP connection, followed by a read that will not be fulfilled until after the data from the second write has reached the destination, experience a constant delay of up to 500 milliseconds, the "[[ACK (TCP)|ACK]] delay". It is recommended to disable either, although traditionally it's easier to disable Nagle, since such a switch already exists for real-time applications.
A solution recommended by Nagle, is tothat avoidprevents the algorithm sending premature packets, is by buffering up application writes and then flushing the buffer:<ref>{{citation | url=http://developers.slashdot.org/comments.pl?sid=174457&threshold=1&commentsort=0&mode=thread&cid=14515105 | title=Boosting Socket Performance on Linux | publisher=Slashdot | author=John Nagle | date=January 19, 2006}}</ref>
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The user-level solution is to avoid write–write–read sequences on sockets. Write–read–write–read is fine. Write–write–write is fine. But write–write–read is a killer. So, if you can, buffer up your little writes to TCP and send them all at once. Using the standard UNIX I/O package and flushing write before each read usually works.
</blockquote>
Nagle considers delayed ACKs a "bad idea", since the application layer does not usually respond within the delay window (which would allow the ACK to be combined with the response packet).<ref>{{cite web|last1=Nagle|first1=John|title=Sigh. If you're doing bulk file transfers, you never hit that problem. (reply 9048947)|url=https://news.ycombinator.com/item?id=9048947|website=Hacker News|accessdate=9 May 2018}}</ref> For typical (non-realtime) use cases, he recommends disabling "delayed ACK" instead of disabling his algorithm, as "quick" ACKs do not incur as much overhead as many small packets do for the same improvement in round-trip time.<ref name=hn9050645>{{cite web|last1=Nagle|first1=John|title=That fixed 200ms ACK delay timer was a horrible mistake. Why 200ms? Human reaction time. (reply 9050645)|url=https://news.ycombinator.com/item?id=9050645|website=Hacker News|accessdate=9 May 2018|quote=[...] One of the few legit cases for turning off the Nagle algorithm is for a FPS game running over the net. There, one-way latency matters; getting your shots and moves to the server before the other players affects gameplay.}}</ref>
