Between-systems memory interference model: Difference between revisions

Revision as of 23:16, 24 November 2023

Revision as of 16:43, 19 April 2024

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== Impact ==

Studying between-systems interference could potentially provide further insight to understanding and treating amnesia. Specifically [[retrograde amnesia]], where there is an inability to recall past memories, may be seen as the hippocampus interfering with the retrieval of memories from the non-hippocampal systems.<ref name="post" /><ref name="best" /> If damage or inactivation of the HPC was induced and if the non-HPC systems were strengthened, perhaps these memories could be retrieved and recalled. However, before reaching this stage of application, more work needs to be done to understand the complexity of the non-HPC systems. This vein of research could potentially lead to more neuropsychological assessments to evaluate their functioning, just as there are tests for HPC functioning. Additionally, if memories can become independent of the HPC, maybe this effect is a two-way transformation pathway such that memories in contextual fear conditioning can become dependent on the HPC again.

One of the major implications that this model illustrates is the dominant effects of the hippocampus on non-hippocampal networks when information is incongruent. With this information in mind, future directions could lead towards the study of these non-hippocampal memory systems through hippocampal inactivation, further expanding the labile constructs of memory. Additionally, many theories of memory are holistically based around the hippocampus. This model could add beneficial information to hippocampal research and memory theories such as the [[multiple trace theory]]. Lastly, the between-system memory interference model allows researchers to evaluate their results on a [[Systems neuroscience|multiple-systems model]], suggesting that some effects may not be simply mediated by one portion of the brain.