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Line 22: === Formation of C3-convertase. === Surface -bound C4b acts as a receptor for the binding of C2.<ref name=":1" /> The binding of C2 and C4b results in C2 being cleaved by C1s into C2a and C2b. ~~C2a~~C2b diffuses into the plasma as a protein inflammatory mediator while ~~C2b~~C2a remains attached with C4b, forming ~~C4bC2b what is known as~~the C3-convertase, (C4b2a). The function of the membrane-bound C3-convertase is the cleavage of many many molecules of C3 into C3a and C3b. C3a is a smaller fragment of C3 is a potent inflammatory mediator. === C3b function and structure. ===

Classical complement pathway: Difference between revisions