Genetic map function: Difference between revisions

Revision as of 22:16, 4 November 2024

Revision as of 22:17, 4 November 2024

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=== Overview ===

Two properties of the Haldane Mapping Function is that it limits recombination frequency up to, but not beyond 50%, and that it represents a linear relationship between the frequency of recombination and map distance up to recombination frequencies of 10%.<ref>{{Cite web |title=mapping function |url=https://www.oxfordreference.com/display/10.1093/oi/authority.20110803100132641 |access-date=2024-04-29 |website=Oxford Reference |language=en |doi=10.1093/oi/authority.20110803100132641 |doi-broken-date=1 November 2024 }}</ref> It also assumes that crossovers occur at random positions and that they do so independent of one another. This assumption therefore also assumes no [[crossover interference]] takes place;<ref name=":1">{{Cite book |title=Mammalian genomics |date=2005 |publisher=CABI Pub |isbn=978-0-85199-910-4 |editor-last=Ruvinsky |editor-first=Anatoly |___location=Wallingford, Oxfordshire, UK ; Cambridge, MA, USA |pages=15 |editor-last2=Graves |editor-first2=Jennifer A. Marshall}}</ref> but using this assumption allows Haldane to model the mapping function using a [[Poisson distribution]].<ref name=":0" />

=== Definitions ===