DNA computing: Difference between revisions

Revision as of 00:36, 10 January 2025

Revision as of 00:50, 10 January 2025

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</ref> machines, respectively; Stojanovic has also demonstrated logic gates using the 8-17 DNAzyme.<ref>

{{Cite journal |last1=Stojanovic |first1=M. N. |last2=Mitchell |first2=T. E. |last3=Stefanovic |first3=D. |year=2002 |title=Deoxyribozyme-Based Logic Gates |url=https://figshare.com/articles/Deoxyribozyme-Based_Logic_Gates/3638808 |journal=Journal of the American Chemical Society |volume=124 |issue=14 |pages=3555–3561 |doi=10.1021/ja016756v |pmid=11929243|bibcode=2002JAChS.124.3555S }}. Also available at [http://www.dna.caltech.edu/courses/cs191/paperscs191/stojanovic_mitchell_stefanovic2002.pdf]

</ref> While these DNAzymes have been demonstrated to be useful for constructing logic gates, they are limited by the need forof a metal cofactor to function, such as Zn²⁺ or Mn²⁺, and thus are not useful [[in vivo]].<ref name="weiss" /><ref>

{{Cite journal | last1 = Cruz | first1 = R. P. G. | last2 = Withers | first2 = J. B. | last3 = Li | first3 = Y. | title = Dinucleotide Junction Cleavage Versatility of 8-17 Deoxyribozyme | doi = 10.1016/j.chembiol.2003.12.012 | journal = Chemistry & Biology | volume = 11 | issue = 1 | pages = 57–67 | year = 2004 | pmid = 15112995| doi-access = free | hdl = 11375/23673 | hdl-access = free }}

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