SOS response: Difference between revisions

Revision as of 05:08, 29 November 2005

Revision as of 13:57, 5 January 2006

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As a result of these properties, some genes may be partially induced in response to even endogenous levels of DNA damage, while other genes appear to be induced only when high or persistent DNA damage is present in the cell.

The SOS response was discovered and named by Miroslav Radman in 19751974 (Radman, M. (1975) SOS repair hypothesis:1974. Phenomenology of an inducible mutagenic DNA repair whichpathway isin accompaniedEscherichia bycoli: SOS repair hypothesis, p. 128-142. In L. Prokash, F. Sherman, M. Miller, C. Lawrence, and H. W. Tabor (ed.), Molecular and environmental aspects of mutagenesis. '''''BasicCharles LifeC Sci'''''Thomas 5A:Publisher, 355–367Springfield, Ill.). He is now Professor at the Faculté de Médecine - Necker, Université Paris V, Paris, France.

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