X-linked dominant inheritance: Difference between revisions

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'''X-linked dominant''' inheritance, sometimes referred to as '''X-linked dominance''', is a mode of [[genetics|genetic inheritance]] by which a [[dominant gene]] is carried on the [[X chromosome]]. As an inheritance pattern, it is less common than the [[X-linked recessive]] type. In medicine, X-linked dominant inheritance indicates that a gene responsible for a [[genetic disorder]] is located on the X chromosome, and only one copy of the gene is sufficient to cause the disorder when inherited from a parent who has the disorder.

== Inheritance ==

As the X chromosome is one of the [[sex chromosome]]s (the other being the [[Y chromosome]]), X-linked

inheritance is determined by the [[gender]] of the parent carrying a specific gene and can often seem complex. This is due to the fact that, typically, [[female]]s have two copies of the X-chromosome, while [[male]]s have only one copy. The difference between [[Dominance (genetics)#Dominant trait|dominant]] and [[Dominance (genetics)#Recessive|recessive]] inheritance patterns also plays a role in determining the chances of a child inheriting an X-linked disorder from their parentage.

==Genetics==

== =Inheritance ===

Males are normally [[Zygosity#Hemizygous|hemizygous]] for the X chromosome, having only one copy. As a result, X-linked dominant disorders usually show higher [[expressivity]] in males than females.<ref name=hex91>{{cite pmid|2018074}}</ref>

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==References==

{{reflist}}

<references/>

{{X-linked disorders}}