Mitochondrial translational release factor 1: Difference between revisions

Revision as of 18:46, 16 May 2010

Revision as of 04:07, 1 June 2010

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{{PBB|geneid=9617}}

'''Mitochondrial translational release factor 1''', also known as '''MTRF1''' is a human [[gene]].<ref name="pmid9838146">{{cite journal | author = Zhang Y, Spremulli LL | title = Identification and cloning of human mitochondrial translational release factor 1 and the ribosome recycling factor | journal = Biochimica et biophysicaBiophysica actaActa | volume = 1443 | issue = 1-2 | pages = 245–50 | year = 1998 | month = November | pmid = 9838146 | doi = 10.1016/S0167-4781(98)00223-1 | url = | issn = }}</ref><ref name="pmid10773675">{{cite journal | author = Hansen LL, Jørgensen R, Justesen J | title = Assignment of the human mitochondrial translational release factor 1 (MTRF1) to chromosome 13q14.1→q14.3 and of the human mitochondrial ribosome recycling factor (MRRF) to chromosome 9q32→q34.1 with radiation hybrid mapping | journal = Cytogenetics and cellCell geneticsGenetics | volume = 88 | issue = 1-2 | pages = 91–2 | year = 2000 | pmid = 10773675 | doi = 10.1159/000015494 | url = | issn = }}</ref>

The [[protein]] encoded by this gene directs the termination of [[Translation (biology)|translation]] in response to the peptide chain [[Stop codon|termination codons]]. Initially thought to have a role in the termination of [[Mitochondrion|mitochondria]] protein synthesis.

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*{{cite journal |author=Nozaki Y, Matsunaga N, Ishizawa T, ''et al.'' |title=HMRF1L is a human mitochondrial translation release factor involved in the decoding of the termination codons UAA and UAG. |journal=Genes Cells |volume=13 |issue= 5 |pages= 429–38 |year= 2008 |pmid= 18429816 |doi= 10.1111/j.1365-2443.2008.01181.x }}

*{{cite journal |author=Dunham A, Matthews LH, Burton J, ''et al.'' |title=The DNA sequence and analysis of human chromosome 13. |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379 |pmc=2665288 }}

*{{cite journal |author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res.Research |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928 }}

*{{cite journal |author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat.Nature Genet.Genetics |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}

*{{cite journal |author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc.Proceedings Natl.of Acad.the Sci.National U.S.A.Academy of Sciences |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241 }}

*{{cite journal |author=Soleimanpour-Lichaei HR, Kühl I, Gaisne M, ''et al.'' |title=mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG. |journal=Mol.Molecular Cell |volume=27 |issue= 5 |pages= 745–57 |year= 2007 |pmid= 17803939 |doi= 10.1016/j.molcel.2007.06.031 |pmc=1976341 }}

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