Short interfering RNA: differenze tra le versioni

Versione delle 19:28, 4 ago 2006

Versione delle 19:28, 4 ago 2006

Riga 39:

==Bibliografia==

<references/>

* {{en}} [http://www.nature.com/nature/journal/v431/n7006/full/nature02870.html Unlocking the potential of the human genome with RNA interference], -articolo aintroduttivo goodapparso introductorysu review article]''Nature''.

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* {{en}} [http://www.nature.com/nature/journal/v391/n6669/abs/391806a0_fs.html Potent and specific genetic interference by double-stranded RNA in ''Caenorhabditis elegans''], -l'articolo theche originalriporta paperdella byprima scoperta della RNAi, ad opera di Fire ''et. al''. describing RNAi]

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* {{en}} [http://www.genesdev.org/cgi/content/full/15/2/188 RNA interference is mediated by 21- and 22-nucleotide RNAs]

*[http://www.nature.com/nature/journal/v431/n7006/full/nature02870.html Unlocking the potential of the human genome with RNA interference - a good introductory review article]

* {{en}} [http://www.cell.com/content/article/abstract?uid=PIIS0092867400806200 RNAi: Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals]

*[http://www.nature.com/nature/journal/v391/n6669/abs/391806a0_fs.html Potent and specific genetic interference by double-stranded RNA in ''Caenorhabditis elegans'' - the original paper by Fire et. al. describing RNAi]

* {{en}} [http://www.nature.com/nbt/journal/v23/n2/abs/nbt1051.html Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy]

*[http://www.genesdev.org/cgi/content/full/15/2/188 RNA interference is mediated by 21- and 22-nucleotide RNAs]

* {{en}} [http://www.blackwell-synergy.com/doi/abs/10.1111/j.1432-0436.2004.07202001.x Determinants of interferon-stimulated gene induction by RNAi vectors]

*[http://www.cell.com/content/article/abstract?uid=PIIS0092867400806200 RNAi: Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals]

* {{en}} [http://www.nature.com/ncb/journal/v5/n9/abs/ncb1038.html Activation of the interferon system by short-interfering RNAs]

Non-specific effects:

*[http://www3.interscience.wiley.com/cgi-bin/abstract/112161228/ABSTRACT?CRETRY=1&SRETRY=0 siRNA binding proteins of microglial cells: PKR is an unanticipated ligand]

*[http://www.nature.com/nbt/journal/v23/n2/abs/nbt1051.html Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy]

*[http://www.biochemsoctrans.org/bst/032/0952/bst0320952.htm RNA interference and double-stranded-RNA-activated pathways]

*[http://www.blackwell-synergy.com/doi/abs/10.1111/j.1432-0436.2004.07202001.x Determinants of interferon-stimulated gene induction by RNAi vectors]

*[http://www.nature.com/ncb/journal/v5/n9/abs/ncb1038.html Activation of the interferon system by short-interfering RNAs]

*[http://www.nature.com/nmeth/journal/v3/n3/abs/nmeth854.html 3' UTR seed matches, but not overall identity, are associated with RNAi off-targets]-->

==Collegamenti esterni==