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The challenge in turn forms part of the UsefulChem project, an ongoing [[open notebook science]] effort to synthesize and screen potential new anti-malarial drugs<ref name="UsefulChem">[http://usefulchem.wikispaces.com/ UsefulChem]</ref>. Data from the Solubility Challenge will be used to build predictive computational models of solubility for use in optimising syntheses<ref name="predictions">[http://rguha.wordpress.com/2009/01/14/ons-solubility-predictions/ ONS solubility modeling and prediction]</ref>.
The challenge began on September 28, 2008<ref name="began">[http://usefulchem.blogspot.com/2008/09/open-notebook-science-challenge.html The beginning of the Open Notebook Science challenge]</ref> and, as of April 2009, involves researchers and their students from at least 4 different institutions<ref name="experiments">[http://onschallenge.wikispaces.com/list+of+experiments List of experiments]</ref> and has resulted in the acquisition of over 400 solubility measurements<ref name=measurements>[
== Prizes ==
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== Request an experiment ==
As well as concentrating on compounds related to the [[Ugi reaction]], the ONSchallenge allows anyone to request a solubility measurement experiment.<ref name="request">[
== Chemical donations ==
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