Kokko and Rector Model: Difference between revisions

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The '''Kokko and Rector model''' is a theory explaining the mechanism of generation of a gradient in the [[inner medulla]] of the [[kidney]]. Unlike earlier theories explaining the mechanism using counter current mechanism (as is the case in the [[outer medulla]]), the driving force for salt reabsorption is stated to be urea accumulation. It has been proved that counter current mechanism cannot be the case in the [[inner medulla]], since there are no salt pumps, and the [[cell membrane]] is too [[Semipermeable membrane|permeable]] to salt.
 
==History==
It has been proposed by JP Kokko and FC Rector Jr.
 
==References==