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is valid for any gradient square lattice.
As the asymmetry coefficient is very sensitive to small changes in the phase and modulus of each gradient vector, it can distinguish complex variability patterns (bilateral asymmetry) even when they are very similar but consist of a very fine structural difference. Note that, unlike most of the statistical tools, the GPA does not rely on the statistical properties of the data but
depends solely on the local symmetry properties of the correspondent gradient pattern.
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