REM Sleep Behavior Disorder Screening Questionnaire: Difference between revisions

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[[Rapid Eye Movement sleep]] Behavior Disorder Screening Questionnaire (RBDSQ) is a specific questionnaire for RBD developed by Stiasny-Kolster and team <ref name=Stiasny-Kolster-RBDSQ>{{cite journal|last=Stiasny-Kolster|first=K|coauthors=Mayer G, Scha¨fer S, Mo¨ller JC, Heinzel-Gutenbrunner M, Oertel WH|title=The REM Sleep Behavior Disorder Screening Questionnaire—A New Diagnostic Instrument.|journal=Movement Disorders|year=2007|volume=22|issue=16|pages=2386–2393|pmid=17894337}}</ref>, to assess the most prominent clinical features of RBD according to the International Classification on Sleep Disorders <ref name=icsd>{{cite journal|last=Atlas Task Force of the American Sleep Disorders Association (ASDA)|title=The International Classification of Sleep Disorders— Diagnostic and Coding Manual.|journal=Minnesota: Rochester|year=2005}}</ref>. It is a 10-item, patient self-rating instrument with short questions to be answered by either 'yes' or 'no' <ref name=Stiasny-Kolster-RBDSQ>{{cite journal|last=Stiasny-Kolster|first=K|coauthors=Mayer G, Scha¨fer S, Mo¨ller JC, Heinzel-Gutenbrunner M, Oertel WH|title=The REM Sleep Behavior Disorder Screening Questionnaire—A New Diagnostic Instrument.|journal=Movement Disorders|year=2007|volume=22|issue=16|pages=2386–2393|pmid=17894337}}</ref>. The validity of the questionnaire was studied by researchers and they have observed it to perform with high sensitivity and reasonable specificity in the diagnosis of RBD <ref>{{cite journal|last=Nomura|first=Takashi|coauthors=Inoue, Yuichi; Kagimura, Tatsuo; Uemura, Yusuke; Nakashima, Kenji|title=Utility of the REM sleep behavior disorder screening questionnaire (RBDSQ) in Parkinson’s disease patients|journal=Sleep Medicine|date=August 2011|volume=12|issue=7|pages=711–713|doi=10.1016/j.sleep.2011.01.015|pmid=21700495}}</ref><ref>{{cite journal|last=Miyamoto|first=Tomoyuki|coauthors=Miyamoto, Masayuki; Iwanami, Masaoki; Kobayashi, Mina; Nakamura, Masaki; Inoue, Yuichi; Ando, Chiharu; Hirata, Koichi|title=The REM sleep behavior disorder screening questionnaire: Validation study of a Japanese version|journal=Sleep Medicine|date=December 2009|volume=10|issue=10|pages=1151–1154|doi=10.1016/j.sleep.2009.05.007|pmid=19604719}}</ref><ref>{{cite journal|last=Nihei|first=Yoshihiro|coauthors=Takahashi, Kazushi; Koto, Atsuo; Mihara, Ban; Morita, Yoko; Isozumi, Kazuo; Ohta, Kouichi; Muramatsu, Kazuhiro; Gotoh, Jun; Yamaguchi, Keiji; Tomita, Yutaka; Sato, Hideki; Seki, Morinobu; Iwasawa, Satoko; Suzuki, Norihiro|title=REM sleep behavior disorder in Japanese patients with Parkinson’s disease: a multicenter study using the REM sleep behavior disorder screening questionnaire|journal=Journal of Neurology|date=10 January 2012|volume=259|issue=8|pages=1606–1612|doi=10.1007/s00415-011-6386-1|pmid=22231870}}</ref> . Although the performance is good, for a definitive diagnosis [[polysomnography]] is required to definitely rule out differential diagnoses such as sleep-related epileptic seizures, non-REM parasomnias (e.g., sleepwalking), obstructive sleep apnea (OSA), or nocturnal periodic leg movements (PLM)<ref name=icsd>{{cite journal|last=Atlas Task Force of the American Sleep Disorders Association (ASDA)|title=The International Classification of Sleep Disorders— Diagnostic and Coding Manual.|journal=Minnesota: Rochester|year=2005}}</ref>.
 
==Contents==
 
RBDSQ conatins a set of 10 items that are to be answered by either 'yes' or 'no'. Items 1 to 4 address the frequency and content of dreams and their relationship to nocturnal movements and behavior. Item 5 asks about self-injuries and injuries of the
bed partner. Item 6 consists of four subitems assessing nocturnal motor behavior more specifically, e.g., questions
about nocturnal vocalization, sudden limb movements, complex movements, or bedding items that fell down. Items 7 and 8 deal with nocturnal awakenings. Item 9 focuses on disturbed sleep in general and item 10 on the presence of any neurological disorder. The maximum total score of the RBDSQ is 13 points.
 
==Applications==
 
RBDSQ has the potential to be useful as a screening instrument for neurodegenerative disorder, such as the α-synucleinopathies, [[Parkinson’s disease]] or [[multiple system atrophy]] which may enable early diagnosis and also recruitment of RBD patients necessary for research studies as well as for therapeutic trials.