C-value: Difference between revisions

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===Human C-values===
The [[Human genome]]<ref name="IHGSC2001">{{cite journal |title=International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome |journal=Nature |volume=409 |pages=860–921 |year=2001 |pmid=11237011 |last1=Lander |first1=ES |last2=Linton |first2=LM |last3=Birren |first3=B |last4=Nusbaum |first4=C |last5=Zody |first5=MC |last6=Baldwin |first6=J |last7=Devon |first7=K |last8=Dewar |first8=K |last9=Doyle |first9=M |last10=Fitzhugh |first10=William |last11=Funke |first11=Roel |last12=Gage |first12=Diane |last13=Harris |first13=Katrina |last14=Heaford |first14=Andrew |last15=Howland |first15=John |last16=Kann |first16=Lisa |last17=Lehoczky |first17=Jessica |last18=Levine |first18=Rosie |last19=McEwan |first19=Paul |last20=McKernan |first20=Kevin |last21=Meldrim |first21=James |last22=Mesirov |first22=Jill P. |last23=Miranda |first23=Cher |last24=Morris |first24=William |last25=Naylor |first25=Jerome |last26=Raymond |first26=Christina |last27=Rosetti |first27=Mark |last28=Santos |first28=Ralph |last29=Sheridan |first29=Andrew |last30=Sougnez |first30=Carrie |issue=6822 |doi=10.1038/35057062|display-authors=8 }}</ref> varies in size; however, the current estimate of the nuclear haploid size of the reference human genome<ref name=GRCh38p2>{{cite web|title=Assembly Statistics for GRCh38.p2 |url=http://www.ncbi.nlm.nih.gov/projects/genome/assembly/grc/human/data |website=Genome Reference Consortium |accessdate=8 February 2015 |date=8 December 2014}}</ref> is 3,031,042,417 bp for the X gamete and 2,932,228,937 bp for the Y gamete. The X gamete and Y gamete both contain 22 autosomes whose combined lengths comprise the majority of the genome in both gametes. The X gamete contains an [[X chromosome]], while the Y gamete contains a [[Y chromosome]]. The larger size of the X chromosome is responsible for the difference in the size of the two gametes. When the gametes are combined, the XX female zygote has a size of 6,062,084,834 bp while the XY male zygote has a size 5,963,271,354 bp. However, the base pairs of the XX female zygote are distributed among 2 homologous groups of 23 heterologous chromosomes each, while the base pairs of the XY male zygote are distributed among 2 homologous groups of 22 heterologous chromosomes each plus 2 heterologous chromosomes. SinceAlthough the XX femaleeach zygote has a46 totalchromosomes, 23 chromosomes of 23the XX female zygote are heterologous while 24 chromosomes whileof the XY male zygote hasare aheterologous. totalAs ofa 24 heterologous chromosomesresult, the C-value for the XX female zygote is 3.099361 while the C-value for the XY male zygote is 3.157877.
 
The human genome's GC content is about 41%.<ref name=Antonarakis>{{cite book|author1=Stylianos E. Antonarakis|authorlink1=Human Genome Sequence and Variation|title=Vogel and Motulsky’s Human Genetics: Problems and Approaches|date=2010|publisher=Springer-Verlag|___location=Berlin Heidelberg|isbn=978-3-540-37654-5|page=32|url=http://www.springer.com/cda/content/document/cda_downloaddocument/9783540376538-c1.pdf?SGWID=0-0-45-855435-p173877407|accessdate=8 February 2015}}</ref> Accounting for the autosomal, X, and Y chromosomes,<ref>{{cite web|last1=Kokocinski|first1=Felix|title=Bioinformatics work notes|url=http://blog.kokocinski.net/index.php/gc-content-of-human-chromosomes?blog=2|website=GC content of human chromosomes|accessdate=8 February 2015}}</ref> human haploid GC contents are 40.97460% for X gametes, and 41.01724% for Y gametes.