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The book criticized a number of hypotheses known at the time, discussed drawbacks of the hypotheses put forth by the authors themselves, and concluded that regardless the suggested mathematical models, the underlying biological mechanisms remain unknown.<ref>"Conclusion" section of the book</ref>
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{{Infobox person
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| name = Leonid A. Gavrilov
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'''Leonid A. Gavrilov''' is a Russian-born American scientist. He is a [[research associate]] at the Center on Aging of the [[National Opinion Research Center]] in [[Chicago]], in the United States. He specializes in the mathematical modeling of aging and mortality, [[biodemography]] and the genetics of aging and longevity. He and his wife Natalia S. Gavrilova have proposed a [[reliability theory of aging]]. Gavrilov has written two books, several chapters and numerous scientific papers.{{Citation needed|date=August 2011}} He is currently a Senior Research Associate at the [[University of Chicago]].
===Biography===
Gavrilov has an [[MSc]] in chemistry (1976) and a [[PhD]] in [[genetics]] (1980), both from [[Moscow State University]]. His book ''The Biology of Life Span: A Quantitative Approach'' was published in Russian in 1986 and in English translation in 1991.<ref name=interview/><ref name=book>Leonid A. Gavrilov, Natalia S. Gavrilova; V.P. Skulachev (ed.); John and Liliya Payne (trans.) (1991). ''The Biology of Life Span: A Quantitative Approach''. Chur; New York: Harwood Academic Publishers. {{ISBN|9783718649839}}.</ref> In 1998 he and his wife emigrated to the United States, where he received a grant from the [[National Institute on Aging]] to study the effects of parental age on lifespan. He taught a course on "biodemography of human mortality and longevity" at the [[University of Chicago]].<ref name=interview/>
Gavrilov is an associate editor of ''[[Experimental Gerontology]]'' and ''[[Theoretical Biology and Medical Modelling]]'', and an editorial board member of ''[[Rejuvenation Research]]'', ''[[Advanced Science Letters]]'' and ''[[The Scientific World Journal]]''. He is a consultant for the [[National Research Council (United States)|National Research Council]] and the National Institute on Aging,<ref name=interview>[s.n.] (2002). [http://online.liebertpub.com/doi/abs/10.1089/109454502321091455?journalCode=rej.1 Pieces of the puzzle: an interview with Leonid A. Gavrilov, PhD]. ''Journal of Anti-Aging Medicine'' '''5''' (3): 255-263.{{self-published-inline|date=September 2015}}</ref> and a fellow of the [[Gerontological Society of America]].
===Publications===
* Leonid A. Gavrilov, Natalia S. Gavrilova; V.P. Skulachev (ed.); John and Liliya Payne (trans.) (1991). ''The Biology of Life Span: A Quantitative Approach''. Chur; New York: Harwood Academic Publishers. {{ISBN|9783718649839}}. (translation of Leonid A. Gavrilov, Natalia S. Gavrilova, V.P. Skulachev (1986). ''Biologiia prodolzhitelʹnosti zhizni: kolichestvennye aspekty'', Moskva: Nauka.)
* Leonid A. Gavrilov, Natalia S. Gavrilova (2001). [http://www.sciencedirect.com/science/article/pii/S0022519301924300 The Reliability Theory of Aging and Longevity]. ''Journal of Theoretical Biology'' '''213''': (4): 527-545.
* {{long dash}} (2004). [http://onlinelibrary.wiley.com/doi/10.1196/annals.1297.094/abstract The Reliability-Engineering Approach to the Problem of Biological Aging]. ''Annals of the New York Academy of Sciences'' '''1019''' (1): 509–512.
* {{long dash}} (2006). [http://www.sciencedirect.com/science/article/pii/B9780120883875500042 Reliability Theory of Aging and Longevity]. In: Edward J. Masoro and Steven N. Austad (2006). ''Handbook of the Biology of Aging'', sixth edition. Burlington, Massachusetts: Academic Press. {{ISBN|9780120883875}}.
==See also==
• [[DNA damage theory of aging]]
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