SNP array: Difference between revisions

Content deleted Content added
Maonao (talk | contribs)
m Shortened author list on 1000 Genomes Project paper
Maonao (talk | contribs)
Principles: Added a reference
Line 5:
==Principles==
{{Unreferenced section|date=April 2015}}
The basic principles of SNP array are the same as the DNA microarray. These are the convergence of [[DNA hybridization]], [[fluorescence microscope|fluorescence microscopy]], and solid surface DNA capture. The three mandatory components of the SNP arrays are:<ref>{{cite journal|last1=LaFramboise|first1=T.|title=Single nucleotide polymorphism arrays: a decade of biological, computational and technological advances|journal=Nucleic Acids Research|date=1 July 2009|volume=37|issue=13|pages=4181–4193|doi=10.1093/nar/gkp552}}</ref>
# An array containing immobilized [[allele-specific oligonucleotide]] (ASO) probes.
# Fragmented [[nucleic acid]] sequences of target, labelled with fluorescent dyes.