X-linked dominant inheritance: Difference between revisions

Revision as of 22:42, 4 January 2018

Revision as of 06:10, 24 January 2018

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'''X-linked dominant inheritance''', sometimes referred to as '''X-linked dominance''', is a mode of [[genetics|genetic inheritance]] by which a [[dominant gene]] is carried on the [[X chromosome]]. As an inheritance pattern, it is less common than the [[X-linked recessive inheritance|X-linked recessive]] type. In medicine, X-linked dominant inheritance indicates that a gene responsible for a [[genetic disorder]] is located on the X chromosome, and only one copy of the [[allele]] is sufficient to cause the disorder when inherited from a parent who has the disorder.

X-linked dominant traits do not necessarily affect males more than females (unlike [[X-linked recessive]] traits). The exact pattern of inheritance varies, depending on whether the father or the mother has the trait of interest. All daughters of an affected father will also be affected but none of his sons will be affected (unless the mother is also affected). In addition, the mother of an affected son is also affected (but not necessarily the other way round).