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Unlike [[difference in differences]] approaches, this method can account for the effects of [[confounder]]s changing over time, by weighting the control group to better match the treatment group before the intervention.<ref name=he>{{cite journal|last1=Kreif|first1=Noémi|last2=Grieve|first2=Richard|last3=Hangartner|first3=Dominik|last4=Turner|first4=Alex James|last5=Nikolova|first5=Silviya|last6=Sutton|first6=Matt|title=Examination of the Synthetic Control Method for Evaluating Health Policies with Multiple Treated Units|journal=Health Economics|date=December 2016|volume=25|issue=12|pages=1514–1528|doi=10.1002/hec.3258}}</ref> Another advantage of the synthetic control method is that it allows researchers to systematically select comparison groups.<ref name=ajps>{{cite journal|last1=Abadie|first1=Alberto|last2=Diamond|first2=Alexis|last3=Hainmueller|first3=Jens|title=Comparative Politics and the Synthetic Control Method|journal=American Journal of Political Science|date=February 2015|volume=59|issue=2|pages=495–510|doi=10.1111/ajps.12116}}</ref> It has been applied to the fields of [[political science]],<ref name=ajps/> [[health policy]],<ref name=he/> [[criminology]],<ref>{{cite journal|last1=Saunders|first1=Jessica|last2=Lundberg|first2=Russell|last3=Braga|first3=Anthony A.|last4=Ridgeway|first4=Greg|last5=Miles|first5=Jeremy|title=A Synthetic Control Approach to Evaluating Place-Based Crime Interventions|journal=Journal of Quantitative Criminology|date=3 June 2014|volume=31|issue=3|pages=413–434|doi=10.1007/s10940-014-9226-5}}</ref> and [[economics]].<ref>{{cite journal|last1=Billmeier|first1=Andreas|last2=Nannicini|first2=Tommaso|title=Assessing Economic Liberalization Episodes: A Synthetic Control Approach|journal=Review of Economics and Statistics|date=July 2013|volume=95|issue=3|pages=983–1001|doi=10.1162/REST_a_00324}}</ref>
The synthetic control method combines elements from [[Matching (statistics)|matching]] and [[difference-in-
The synthetic control method tries to offer a more systematic way to assign weights to the control group. It typically uses a relatively long time series of the outcome prior to the intervention and estimates weights in such a way that the control group mirrors the treatment group as closely as possible. In particular, assume we have ''J'' observations over ''T'' time periods where the relevant treatment occurs at time
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