Role of cell adhesions in neural development: Difference between revisions

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==Adhesions role in cell migration ==
During early development, cell migration plays a crucial role in neuronal tissue organization. Although still largely under investigation, networks of highly ordered neurons are known to be a vital component of the nervous systems communication with the body. A major mechanism of cellular migration is the translation of internal force, to the external environment. Force transmission can occur through a variety of mechanisms, though adhesion complexes between cell-cell and cell-extracellular matrix (ECM) are a known to be chief mechanisms of this activity.<ref>{{cite journal|last=Ridley|first=Anne|title=Cell Migration: Integrating Signals from Front to Back|journal=Science|year=2003|volume=302|issue=2003|pages=1704–09|doi=10.1126/science.1092053|pmid=14657486|url=http://cdr.lib.unc.edu/downloads/x059c962f}}</ref> Cell migration is generally classified with four cell processes:
# Leading edge protrusion
# Adhesion formation