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| first4 = M. | last4 = Rudzsky | title = Fast geodesic active contours | journal = IEEE Transactions on Image Processing | year = 2001
| volume = {10 | pages = 1467-1475 | issue = 10}}</ref> for rapid computation of this segmentation method. The uniqueness and existence of this
combined model were proven in 
| title = Existence and uniqueness results for the gradient vector flow and geodesic active contours mixed model |
journal = Communications on Pure and Applied Analysis | year = 2009 | volume = 8 | issue = 4 | pages = 1333-1349}}</ref>.
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to achieve even better segmentation for images with complex geometric objects.
GVF has been used to find both inner, central, and central cortical surfaces in the analysis of brain images <ref name=":HanxNI04"/>, as shown in Figure 4. The
process first finds the inner surface using a three-dimensional geometric deformable model with conventional forces. Then the central▼
surface is found by exploiting the central tendency property of GVF. In particular, the cortical membership function of the human brain▼
cortex, derived using a fuzzy classifier, is used to compute GVF as if itself were a thick edge map. The computed GVF vectors point towards▼
the center of the cortex and can then be used as external forces to drive the inner surface to the central surface. Finally, another▼
▲geometric deformable model with conventional forces. Then the central
geometric deformable model with conventional forces is used to drive the central surface to a position on the outer surface of the cortex.▼
▲surface is found by exploiting the central tendency property of GVF.
▲cortex, derived using a fuzzy classifier, is used to compute GVF as if
▲the center of the cortex and can then be used as external forces to
▲the central surface to a position on the outer surface of the cortex.
Several notable recent applications of GVF include constructing graphs for optimal surface segmentation in spectral-___domain optical coherence
tomography volumes
of interest in ultrasound image segmentation
▲tomography volumes~\cite{MirxCMIG17}, a learning based probabilistic GVF active contour
for improved ultrasound image segmentation without hand tuned paramaters <ref name=":RodxJVCIR13>{{Cite journal | title=Multi-feature gradient vector flow snakes for adaptive segmentation of the ultrasound images of breast cancer | last1 = Rodtook | first1 = A. | last2 = Makhanov | first2 = S.S. | journal=Journal of Visual Communication and Image Representation | volume=24 | issue = 8 | pages=1414-1430 | year=2013 | publisher=Elsevier}}</ref>
▲segmentation~\cite{HafxCBM14}, and an adaptive multi-feature GVF active contour
==Related Concepts==
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