Pulmonary function testing: Difference between revisions

Revision as of 04:54, 10 October 2020

Revision as of 20:48, 3 December 2020

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===Pediatric neuromuscular disorders===

Neuromuscular disorders such as [[Duchenne muscular dystrophy]] are associated with gradual loss of muscle function over time. Involvement of respiratory muscles results in poor ability to cough and decreased ability to breathe well and leads to [[atelectasis|collapse of part or all of the lung]] leading to impaired gas exchange and an overall insufficiency in lung strength.<ref>Finder JD, Birnkrant D, Carl J, et al. Respiratory care of the patients with Duchenne muscular dystrophy: ATS consensus statement. Am J Respir Crit Care Med.2004;170 (4):456– 465</ref> Pulmonary function testing in patients with neuromuscular disorders helps to evaluate the respiratory status of patients at the time of diagnosis, monitor their progress and course, evaluate them for possible surgery, and gives an overall idea of the prognosis.<ref name="pmid19420147">{{cite journal| author=Sharma GD| title=Pulmonary function testing in neuromuscular disorders. | journal=Pediatrics | year= 2009 | volume= 123 Suppl 4 | issue= | pages= S219–21 | pmid=19420147 | doi=10.1542/peds.2008-2952D | pmc= | doi-access=free }}</ref>

==Measurements==

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===Oxygen desaturation during exercise===

The [[six-minute walk test]] is a good index of physical function and therapeutic response in patients with [[chronic lung disease (disambiguation)|chronic lung disease]], such as [[COPD]] or [[idiopathic pulmonary fibrosis]].<ref name="pmid12890299">{{cite journal| author=Enright PL| title=The six-minute walk test. | journal=Respir Care | year= 2003 | volume= 48 | issue= 8 | pages= 783–5 | pmid=12890299 | doi= | pmc= | url= }}</ref><ref name="pmid19996335">{{cite journal |vauthors=Swigris JJ, Wamboldt FS, Behr J, du Bois RM, King TE, Raghu G, etal | title=The 6 minute walk in idiopathic pulmonary fibrosis: longitudinal changes and minimum important difference. | journal=Thorax | year= 2010 | volume= 65 | issue= 2 | pages= 173–7 | pmid=19996335 | doi=10.1136/thx.2009.113498 | pmc=3144486}}</ref><ref name="pmid12091180">{{cite journal| author=ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories| title=ATS statement: guidelines for the six-minute walk test. | journal=Am J Respir Crit Care Med | year= 2002 | volume= 166 | issue= 1 | pages= 111–7 | pmid=12091180 | doi= 10.1164/ajrccm.166.1.at1102| pmc= | url= }}</ref>

===Arterial blood gases===