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| DIAMOND
| BLASTX and BLASTP aligner based on double indexing || Protein || Buchfink B, Xie C, Huson DH, Reuter K, Drost HG <ref>{{Cite journal |author=Buchfink, Xie and Huson |title=Fast and sensitive protein alignment using DIAMOND |journal=Nature Methods |volume=12 |issue=1 |pages=59–60 |date= 2015 |doi=10.1038/nmeth.3176|pmid=25402007 |s2cid=5346781 }}</ref><ref>{{Cite journal |author=B Buchfink, K Reuter and HG Drost |title=Sensitive protein alignments at tree-of-life scale using DIAMOND |journal=Nature Methods |volume=18 |pages=366–368 |date= 2021 |issue=4 |doi=10.1038/s41592-021-01101-x|pmid=33828273 |pmc=8026399 |doi-access=free }}</ref>
|| 2015/2021
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! Sequence type*
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| EAGLE <ref name="Pratas2020">{{cite journal|last1=Pratas|first1=Diogo|last2=Silva|first2=Jorge|title=Persistent minimal sequences of SARS-CoV-2|journal=Bioinformatics|year=2020|volume=36|issue=21|pages=5129–5132|doi=10.1093/bioinformatics/btaa686|pmid=32730589|pmc=7559010|doi-access=free}}</ref>
| An ultra-fast tool to find relative absent words in genomic data
| Nucleotide
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