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{{short description|Statistical technique to use observational data for causal analysis}}
'''Difference in differences''' ('''DID'''<ref>{{cite journal |last=Abadie |first=A. |year=2005 |title=Semiparametric difference-in-differences estimators |journal=[[Review of Economic Studies]] |volume=72 |issue=1 |pages=1–19 |doi=10.1111/0034-6527.00321 |citeseerx=10.1.1.470.1475 }}</ref> or '''DD'''<ref name=Bertrand>{{cite journal |last1=Bertrand |first1=M. |last2=Duflo |first2=E. |author-link2=Esther Duflo |last3=Mullainathan |first3=S. |year=2004 |title=How Much Should We Trust Differences-in-Differences Estimates? |journal=[[Quarterly Journal of Economics]] |volume=119 |issue=1 |pages=249–275 |doi=10.1162/003355304772839588 |s2cid=470667 |url=http://www.nber.org/papers/w8841.pdf }}</ref>) is a [[statistics|statistical technique]] used in [[econometrics]] and [[quantitative research]] in the social sciences that attempts to mimic an [[experiment|experimental research design]] using [[observational study|observational study data]], by studying the differential effect of a treatment on a 'treatment group' versus a '[[control group]]' in a [[natural experiment]].<ref>{{cite book |last1=Angrist |first1=J. D. |last2=Pischke |first2=J. S. |year=2008 |title=Mostly Harmless Econometrics: An Empiricist's Companion |publisher=Princeton University Press |isbn=978-0-691-12034-8 |pages=227–243 |url=https://books.google.com/books?id=ztXL21Xd8v8C&pg=PA227 }}</ref> It calculates the effect of a treatment (i.e., an explanatory variable or an [[independent variable]]) on an outcome (i.e., a response variable or [[dependent variable]]) by comparing the average change over time in the outcome variable for the treatment group
In contrast to a [[time series|time-series estimate]] of the treatment effect on subjects (which analyzes differences over time) or a cross-section estimate of the treatment effect (which measures the difference between treatment and control groups), difference in differences uses [[panel data]] to measure the differences, between the treatment and control group, of the changes in the outcome variable that occur over time.
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