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===SSAP===
SSAP (sequential structure alignment program) is a dynamic programming-based method of structural alignment that uses atom-to-atom vectors in structure space as comparison points. It has been extended since its original description to include multiple as well as pairwise alignments,<ref name=taylor>{{cite journal|journal=Protein Sci |volume=3 |pages=1858–70 |year=1994 |author1=Taylor WR |author2=Flores TP |author3=Orengo CA. |title=Multiple protein structure alignment |url=http://www.proteinscience.org/cgi/pmidlookup?view=long&pmid=7849601 |pmid=7849601 |doi=10.1002/pro.5560031025 |issue=10 |pmc=2142613 }}{{dead link|date=September 2016|bot=InternetArchiveBot |fix-attempted=yes }}</ref> and has been used in the construction of the [[CATH]] (Class, Architecture, Topology, Homology) hierarchical database classification of protein folds.<ref name=orengo>{{cite journal | journal=Structure | volume=5 | pages=1093–108 | year=1997 |author1=Orengo CA |author2=Michie AD |author3=Jones S |author4=Jones DT |author5=Swindells MB |author6=Thornton JM | title=CATH--a hierarchic classification of protein ___domain structures | pmid=9309224 | doi=10.1016/S0969-2126(97)00260-8 | issue=8 | doi-access=free }}</ref> The CATH database can be accessed at [http://www.cathdb.info/ CATH Protein Structure Classification].
===Combinatorial extension===
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