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* [[IBM]] Automatic Binary Optimizer for z/OS (ABO)Trial Cloud Service (2020)<ref>https://optimizer.ibm.com</ref>
* [[The Sun Studio Binary Code Optimizer]]<ref>http://developers.sun.com/solaris/articles/binopt.html</ref> - which requires a [[software performance analysis|profile]] phase beforehand
* Design and Engineering of a Dynamic Binary Optimizer - from [[IBM]] T. J. Watson Res. Center (February 2005)<ref>{{Cite journal |doi = 10.1109/JPROC.2004.840302|title = Design and Engineering of a Dynamic Binary Optimizer|year = 2005|last1 = Duesterwald|first1 = E.|journal = Proceedings of the IEEE|volume = 93|issue = 2|pages = 436–448|s2cid = 2217101}}</ref><ref>http://portal.acm.org/citation.cfm?id=1254810.1254831</ref>
* QuaC: Binary Optimization for Fast [[self-modifying code|Runtime Code Generation]] in [[C (programming language)|C]]<ref>http://www.eecs.berkeley.edu/Pubs/TechRpts/1994/CSD-94-792.pdf</ref> - (which appears to include some elements of JIT)
* [[DynamoRIO]]
* COBRA: An Adaptive Runtime Binary Optimization Framework for Multithreaded Applications<ref>{{Cite book | doi=10.1109/ICPP.2007.23| isbn=978-0-7695-2933-2| chapter=COBRA: An Adaptive Runtime Binary Optimization Framework for Multithreaded Applications| title=2007 International Conference on Parallel Processing (ICPP 2007)| year=2007| last1=Kim| first1=Jinpyo| last2=Hsu| first2=Wei-Chung| last3=Yew| first3=Pen-Chung| pages=25| s2cid=15079211}}</ref>
* Spike Executable Optimizer (Unix kernel)<ref>http://www.cesr.ncsu.edu/fddo4/papers/spike_fddo4.pdf</ref>
* [https://web.archive.org/web/20160214082946/http://www.cs.arizona.edu/solar/ "SOLAR" Software Optimization at Link-time And Run-time]
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